Testing advanced 7-Tesla MRI for better imaging of muscles and the brain
Explorative Technical Feasibility Testing of 7-Tesla Magnetic Resonance Imaging of the Musculoskeletal System and of the Head
NA · Balgrist University Hospital · NCT05992298
This study is testing whether a stronger 7-Tesla MRI can give clearer images of muscles and the brain compared to the standard 3-Tesla MRI for people with various conditions.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 780 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Balgrist University Hospital (other) |
| Locations | 1 site (Zurich, Canton of Zurich) |
| Trial ID | NCT05992298 on ClinicalTrials.gov |
What this trial studies
This project aims to assess the technical feasibility of using a 7-Tesla magnetic resonance imaging (MRI) scanner to non-invasively image the human musculoskeletal system and head. The study will compare the image quality of the investigational 7T MRI with standard 3T MRI images to determine the advantages of the higher field strength. Participants will undergo MRI exams to evaluate the qualitative improvements in imaging for various conditions affecting muscles, tendons, and the brain.
Who should consider this trial
Good fit: Ideal candidates include individuals with specific musculoskeletal or neurological conditions who can consent to undergo MRI exams.
Not a fit: Patients with contraindications to MRI, irregular anatomy, or those unable to comply with study procedures may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to significantly improved imaging techniques that enhance diagnosis and treatment planning for musculoskeletal and neurological conditions.
How similar studies have performed: While the use of 7T MRI is relatively novel, previous studies have indicated potential benefits in image quality, suggesting a promising avenue for further exploration.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Consent to undergo a 7T (and, if appropriate a comparative 3T) MRI exam. * For some of the consistent small series: presence of a specific condition of the musculoskeletal system or of the head. This can include traumatic or degenerative changes, e.g., of tendons, cartilage, muscle, peripheral nerves, ligaments, and bones, or in the brain, as well as focal lesions, e.g., tumors. Exclusion Criteria: * Contraindications to undergo a MRI examination at a field strength of 7 Tesla or at 3 Tesla. * Irregular anatomy and/or tissue properties * Inability to consent - for any reason. * Body mass above 200 kg. * Body mass below 30 kg. * Women: pregnancy. * Age below 18. * Known or suspected non-compliance, drug or alcohol abuse. * Inability to follow the procedures of the study.
Where this trial is running
Zurich, Canton of Zurich
- Balgrist University Hospital — Zurich, Canton of Zurich, Switzerland (RECRUITING)
Study contacts
- Principal investigator: Reto Sutter, Prof. — Balgrist University Hospital
- Study coordinator: Reto Sutter, Prof.
- Email: reto.sutter@balgrist.ch
- Phone: +41 44 386 33 08
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Magnetic Resonance Imaging