Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Testing advanced 7-Tesla MRI for better imaging of muscles and the brain

Official title: Explorative Technical Feasibility Testing of 7-Tesla Magnetic Resonance Imaging of the Musculoskeletal System and of the Head

Run by Balgrist University Hospital · NCT05992298 · Data updated 2026-11-12

This study is testing whether a stronger 7-Tesla MRI can give clearer images of muscles and the brain compared to the standard 3-Tesla MRI for people with various conditions.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment780 (estimated)
SponsorBalgrist University Hospital
Academic / other
Locations1 site (Zurich, Canton of Zurich)
StatusRecruiting
StartedAugust 7, 2023
Main results expectedFebruary 29, 2028
Study endsFebruary 29, 2028
Registry record updatedOctober 2, 2025
Trial IDNCT05992298 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals with specific musculoskeletal or neurological conditions who can consent to undergo MRI exams.

Probably not a fit

Patients with contraindications to MRI, irregular anatomy, or those unable to comply with study procedures may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to assess the technical feasibility of using a 7-Tesla magnetic resonance imaging (MRI) scanner to non-invasively image the human musculoskeletal system and head. The study will compare the image quality of the investigational 7T MRI with standard 3T MRI images to determine the advantages of the higher field strength. Participants will undergo MRI exams to evaluate the qualitative improvements in imaging for various conditions affecting muscles, tendons, and the brain.

Why it matters

Potential benefit: If successful, this study could lead to significantly improved imaging techniques that enhance diagnosis and treatment planning for musculoskeletal and neurological conditions.

How similar studies have gone: While the use of 7T MRI is relatively novel, previous studies have indicated potential benefits in image quality, suggesting a promising avenue for further exploration.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Consent to undergo a 7T (and, if appropriate a comparative 3T) MRI exam.
* For some of the consistent small series: presence of a specific condition of the musculoskeletal system or of the head. This can include traumatic or degenerative changes, e.g., of tendons, cartilage, muscle, peripheral nerves, ligaments, and bones, or in the brain, as well as focal lesions, e.g., tumors.

Exclusion Criteria:

* Contraindications to undergo a MRI examination at a field strength of 7 Tesla or at 3 Tesla.
* Irregular anatomy and/or tissue properties
* Inability to consent - for any reason.
* Body mass above 200 kg.
* Body mass below 30 kg.
* Women: pregnancy.
* Age below 18.
* Known or suspected non-compliance, drug or alcohol abuse.
* Inability to follow the procedures of the study.

Where it's running

  • Balgrist University Hospital
    Zurich, Canton of Zurich, Switzerland
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.