Testing a zinc oxide device for securing catheters in hospitalized adults

Effectiveness of a Zinc Oxide Adhesive Securement Device in the Fixation of Midline and Peripherally Inserted Central Catheters in Hospitalized Adult Patients: Randomised Clinical Trial

NA · Hospital Arnau de Vilanova · NCT06770374

This study is testing whether a zinc oxide adhesive can help keep catheters in place and reduce problems for adults in the hospital who need catheterization.

Quick facts

PhaseNA
Study typeInterventional
Enrollment400 (estimated)
Ages18 Years and up
SexAll
SponsorHospital Arnau de Vilanova (other)
Locations2 sites (Lleida, Catalonia and 1 other locations)
Trial IDNCT06770374 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of a zinc oxide adhesive securement device in reducing complications associated with midline catheters (MLC) and peripherally inserted central catheters (PICC) in hospitalized adult patients. Participants will be randomly assigned to receive either a zinc oxide or silicone adhesive device for catheter fixation. The aim is to determine if the zinc oxide device can lower the incidence of catheter dislodgement, skin injuries, and other related complications. The study will involve patients who require catheterization and will be monitored for outcomes related to catheter fixation.

Who should consider this trial

Good fit: Ideal candidates are hospitalized adults requiring a midline catheter or PICC for at least 7 days.

Not a fit: Patients with a known allergy to zinc oxide will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce catheter-related complications and improve patient comfort and safety.

How similar studies have performed: While similar studies have explored adhesive devices, the specific use of a zinc oxide device for this purpose is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* requiring cannulation of a midline catheter or a PICC
* who accepted and signed the informed consent voluntarily
* with an inpatient unit admission of minimum 7 days

Exclusion Criteria:

\- patients with a known allergy to zinc oxide

Where this trial is running

Lleida, Catalonia and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Vascular Access Complication, Skin and Subcutaneous Tissue Disorders, Phlebitis, Pain, Catheters, Vascular Access Devices, Catheter-Related Infections, Nurse Specialists

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.