Testing a yellow fever vaccine in healthy adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the safety and efficacy of the YF-17D yellow fever vaccine in healthy adults aged 18-50 years. It aims to address the lack of antiviral treatments for yellow fever, focusing on individuals who are at risk but cannot be vaccinated due to contraindications. The study will involve administering the vaccine and monitoring participants for any adverse effects or immune responses. The ultimate goal is to develop effective treatment options for those unprotected against yellow fever infection.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age 18-50 years

Exclusion Criteria:

* contraindication to receive YF-17D (immune deficiency, thymus illness)
* previous YF vaccination
* pregnancy
* chicken egg allergy
* hypersensitivity to any other substance in the YF-17D vaccine
* interval of \< 4 weeks of another live attenuated vaccine

Where it's running

• Leiden University Medical Center
  Leiden, Netherlands Recruiting

Study contacts

• Principal investigator: Anna HE Roukens, MD PhD — Leiden University Medical Center
• Study coordinator: Anna H Roukens, MD, PhD
• Email: a.h.e.roukens@lumc.nl
• Phone: +31715262613

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.