Testing a tobacco cessation program for American Indian communities

Testing All Nations Snuff Out Smokeless (ANSOS) for Efficacy in Multi-Tribal Urban Communities

Not applicable Interventional Lehigh University · NCT06566703

This study is testing a special program designed to help American Indian people quit using smokeless tobacco by providing support and counseling that respects their culture.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment384 (estimated)
Ages18 Years and up
SexAll
SponsorLehigh University Academic / other
Locations1 site (Bethlehem, Pennsylvania)
Trial IDNCT06566703 on ClinicalTrials.gov

What this trial studies

This trial evaluates the efficacy of the All Nations Snuff Out Smokeless (ANSOS) program, a culturally tailored intervention aimed at helping American Indian individuals quit smokeless tobacco. Participants are randomly assigned to either the ANSOS intervention group, which includes group support sessions and individual counseling, or a wait-list control group receiving a Healthy Living educational intervention. The program incorporates cultural elements and addresses historical trauma and mistrust in medical research. The study aims to engage participants over a 12-month period, with follow-up measures taken at six months.

Who should consider this trial

Good fit: Ideal candidates are American Indian adults aged 18 and over who use smokeless tobacco daily and can participate in Zoom sessions.

Not a fit: Patients who do not have a stable phone number or are unable to attend Zoom sessions may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly improve smokeless tobacco cessation rates among American Indian communities.

How similar studies have performed: Other studies have shown success with culturally tailored tobacco cessation programs, indicating potential for positive outcomes in similar approaches.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 and over
* Stable telephone number that can be used for the purpose of the study
* Willing to be followed for 12 months and participate in study activities
* Able to attend Zoom sessions
* Current SLT user, at least once per day
* Self-reported AI

Exclusion Criteria:

* Cannot provide a stable phone number for 12 months for the purpose of the study
* Unable to attend Zoom sessions

Where this trial is running

Bethlehem, Pennsylvania

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Smokeless Tobacco CessationAmerican Indiansmokeless tobacco cessation
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.