Clinical trial No longer in our active list Interventional

Testing a niacinamide serum for skin hydration and safety

Official title: Testing the Efficacy and Safety of Niacinamide Cosmetic Preparation: A Randomised, Controlled Trial

Run by University of Split, School of Medicine · NCT06189105 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing if a niacinamide serum can improve skin hydration and health for people who are healthy and not using it yet.

Quick facts

Study typeInterventional
SexAll
Enrollment25 (estimated)
SponsorUniversity of Split, School of Medicine
Academic / other
Drugs / interventionsradiation
Locations1 site (Split)
Trial IDNCT06189105 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are healthy volunteers without any skin diseases or conditions that could interfere with the trial.

Probably not a fit

Patients with existing skin diseases, those using corticosteroids or immunomodulators, or pregnant or lactating women may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the efficacy and safety of a niacinamide cosmetic preparation in healthy volunteers. Participants will be randomly assigned to receive either the niacinamide serum or continue with their usual skincare routine. The study aims to assess improvements in skin hydration and overall skin health. The trial will monitor participants for any adverse effects associated with the treatment.

Why it matters

Potential benefit: If successful, this study could provide a new effective cosmetic treatment for improving skin hydration and addressing conditions like hyperpigmentation and eczema.

How similar studies have gone: Other studies have shown positive results with niacinamide in skincare, suggesting this approach may be effective.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* healthy volunteers who gave written informed consent

Exclusion Criteria:

* skin disease, skin damage on measurement sites, use of corticosteroids and immunomodulators a month prior to the inclusion and during the trial, non-adherence to the trial protocol, exposure to artificial UV radiation, pregnancy and lactation

Where it's running

  • University of Split School of Medicine
    Split, Croatia
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.