Testing a niacinamide serum for skin hydration and safety

Testing the Efficacy and Safety of Niacinamide Cosmetic Preparation: A Randomised, Controlled Trial

Not applicable Interventional University of Split, School of Medicine · NCT06189105

This study is testing if a niacinamide serum can improve skin hydration and health for people who are healthy and not using it yet.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment25 (estimated)
SexAll
SponsorUniversity of Split, School of Medicine Academic / other
Drugs / interventionsradiation
Locations1 site (Split)
Trial IDNCT06189105 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the efficacy and safety of a niacinamide cosmetic preparation in healthy volunteers. Participants will be randomly assigned to receive either the niacinamide serum or continue with their usual skincare routine. The study aims to assess improvements in skin hydration and overall skin health. The trial will monitor participants for any adverse effects associated with the treatment.

Who should consider this trial

Good fit: Ideal candidates for this study are healthy volunteers without any skin diseases or conditions that could interfere with the trial.

Not a fit: Patients with existing skin diseases, those using corticosteroids or immunomodulators, or pregnant or lactating women may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a new effective cosmetic treatment for improving skin hydration and addressing conditions like hyperpigmentation and eczema.

How similar studies have performed: Other studies have shown positive results with niacinamide in skincare, suggesting this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* healthy volunteers who gave written informed consent

Exclusion Criteria:

* skin disease, skin damage on measurement sites, use of corticosteroids and immunomodulators a month prior to the inclusion and during the trial, non-adherence to the trial protocol, exposure to artificial UV radiation, pregnancy and lactation

Where this trial is running

Split

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Skin HyperpigmentationDry SkinEczema
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.