Testing a new method for measuring allergy-related IgE levels

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the feasibility of a new specific IgE assay called LuLISA, which utilizes a bioluminescence technique to analyze blood and urine samples from both pediatric and adult patients with allergies. The current standard method, ImmunoCAP, is costly and requires a significant amount of blood, which poses challenges especially for children. By using the LuLISA method, the study seeks to reduce the amount of blood needed and improve the turnaround time for results, potentially allowing for quicker diagnosis and management of allergies. The study will involve collecting samples during routine follow-up visits for allergy patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Males or females 6 months' old or older
* Sensitization or allergy towards a trophallergen, an aeroallergen, hymenoptera venom or drug proven by:

  * positive skin test (s)
  * and / or IgE specific (s)\> 0.1 kUA / L
  * and / or anamnesis in favor of an allergic reaction of mediated IgE
* Social coverage up to date

Exclusion Criteria:

* Children younger than 6 months'old
* Children's weight less than 10 kg
* Pregnant or breastfeeding women
* Patients with cystic fibrosis
* Patients with dysimmune or autoimmune pathology
* Anamnesis in favor of a delayed allergy or a contact allergy.

Where it's running

• University Hospital
  Toulouse, France Recruiting
• Larrey hospital
  Toulouse, France Recruiting

Study contacts

• Principal investigator: Marine Michelet, MD — University Hospital, Toulouse
• Study coordinator: Marine Michelet, MD
• Email: michelet.m@chu-toulouse.fr
• Phone: 33-5 34 55 85 85

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.