Testing a new device for detecting COVID-19 in breath and nasal samples

BIOAEROSOL SAMPLING DEVICE (BSD) CLINICAL STUDY: Performance of Respiratory Pathogen Bioaerosol Sampling Device Compared to Matched Swab Sample With Molecular and Antigen Assays That Can Detect SARS-CoV-2 Phase II Validation

Observational Cantor BioConnect, Inc. · NCT06047067

This study is testing a new device that checks breath and nasal samples for COVID-19 to see if it works better than regular nasal swabs and at-home tests for people aged 5 and older.

Quick facts

Study typeObservational
Enrollment330 (estimated)
Ages5 Years and up
SexAll
SponsorCantor BioConnect, Inc. Research network
Locations6 sites (S. Gate, California and 5 other locations)
Trial IDNCT06047067 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the Bioaerosol Sampling Device (BSD) for its effectiveness in sampling bioaerosols and nasal secretions to detect COVID-19 viral particles. The study will compare the BSD's performance against traditional nasal swab tests using RT-PCR and at-home molecular and antigen assays. By providing a non-invasive and potentially more comfortable testing method, the BSD could enhance early detection of COVID-19 in patients. Participants will include individuals aged 5 and older who are seeking COVID-19 testing, regardless of symptoms.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 5 years or older who are seeking COVID-19 testing and have an unknown COVID-19 status.

Not a fit: Patients who are unable to tolerate nasal sampling or are currently enrolled in other trials involving nasal cavity sampling may not benefit from this study.

Why it matters

Potential benefit: If successful, this device could lead to earlier and more comfortable COVID-19 testing, potentially reducing virus transmission.

How similar studies have performed: While the approach of using bioaerosol sampling is innovative, similar studies have shown promise in enhancing non-invasive testing methods for respiratory viruses.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Any patient 5 years or older who wants to be tested Patients may be symptomatic or asymptomatic based on CDC guidelines Patients may be suspected of having COVID-19 based on CDC guidelines Patient's COVID-19 status should be unknown Patients younger than 12 should be assisted by an adult

Exclusion Criteria:

Unable to self-consent Concurrent enrollment in other trials involving same-day nasal cavity sampling

Contraindication to nasal sampling as performed according to the clinical site policies and procedures, including:

Unable to tolerate Nasal Swab Sampling History of perforation of the nasal septum or prone to nosebleed Head or facial injury/surgery within the past 6 months On anticoagulant therapy including anti-platelet therapy Nasal or nasal aspirate and nasal wash performed as standard of care.

Where this trial is running

S. Gate, California and 5 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions COVID-19Rapid diagnostic testSARS-CoV-2SARS-CoV-1
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.