Testing a new approach to reduce cholera and diarrhea in households
Official title: Testing a Scalable Model of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7)
Run by Johns Hopkins Bloomberg School of Public Health · NCT06498817 · Data updated 2026-11-12
This study is testing a new program to see if better water and hygiene practices can help reduce cholera and diarrhea in homes with young children.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 1600 (estimated) |
| Sponsor | Johns Hopkins Bloomberg School of Public Health Academic / other |
| Locations | 1 site (Mānikganj) |
| Status | Recruiting |
| Started | August 19, 2024 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | April 15, 2026 |
| Trial ID | NCT06498817 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are diarrhea patients with three or more loose stools in the past 24 hours, living without running water, and having a child under five years old in their household.
✕Probably not a fit
Patients who do not have a working mobile phone in their household may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This intervention focuses on the Cholera Hospital-Based Intervention for 7 Days (CHoBI7), which aims to reduce cholera and diarrheal diseases through improved water, sanitation, and hygiene (WASH) practices. The study will tailor the CHoBI7 program for delivery in rural health facilities and assess its feasibility in both urban and rural settings. It will evaluate the effectiveness of providing a modified WASH package that includes a soapy water bottle and chlorine tablets. The goal is to promote sustained handwashing and safe drinking water practices among households with young children.
Why it matters
Potential benefit: If successful, this intervention could significantly reduce the incidence of cholera and diarrheal diseases in vulnerable populations, particularly young children.
How similar studies have gone: Previous studies have shown success with similar WASH interventions, particularly during cholera outbreaks, indicating a promising approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diarrhea patients presenting with three or more loose stools over a 24h period * Having no running water inside of the patient's home * Plan to reside in current residence for the next 3 months * Have a child \<5 years in the patient's household * Have a working mobile phone in the household Exclusion Criteria: * No one will be excluded because of age, sex, religion, or sexual preference
Where it's running
-
Manikganjg Sadar (District) Hospital
Mānikganj, Bangladesh Recruiting
Study contacts
- Principal investigator: Christine Marie George, PhD — Johns Hopkins Bloomberg School of Public Health
- Study coordinator: Christine Marie George, PhD
- Email: cmgeorge@jhu.edu
- Phone: (202) 657-5798
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.