Tenting the Schneiderian membrane of the maxillary sinus using titanium mesh
Clinical, Radiographic and Histologic Evaluation of Tenting the Schneiderian Membrane Using Titanium Mesh for Maxillary Sinus Lift Procedure: A Randomized Controlled Study
NA · Suez Canal University · NCT07035236
This trial will test whether using titanium mesh to lift and tent the sinus membrane improves outcomes for patients needing maxillary sinus floor augmentation for dental implants.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Suez Canal University (other) |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Ismailia) |
| Trial ID | NCT07035236 on ClinicalTrials.gov |
What this trial studies
Twenty posterior maxillary edentulous sites requiring open sinus augmentation for staged dental implant placement will be treated and compared between two mechanical stabilization methods. One group will have the Schneiderian membrane elevated and tented with titanium mesh fixed by bone screws, while the control group will receive conventional stainless steel screws or pins placed bucco-palatally. Platelet-rich fibrin (PRF) will be placed at the elevated membrane site in both groups, and patients will be followed for healing and readiness for implant placement. The study focuses on surgical technique and local tissue response rather than systemic therapies.
Who should consider this trial
Good fit: Adults aged 18–60 with one or more posterior maxillary sites needing implant-supported restorations, alveolar bone height under 5 mm, good oral hygiene, and willing to consent are ideal candidates.
Not a fit: Patients who are medically compromised (for example uncontrolled diabetes or recent chemotherapy/radiation), have active sinus infection, heavy smokers, or untreated periodontal disease are unlikely to benefit or be eligible.
Why it matters
Potential benefit: If successful, this approach could provide more reliable membrane support and better bone fill, making staged implant placement more predictable for patients with severe posterior maxillary atrophy.
How similar studies have performed: Membrane tenting and the use of various meshes have been reported in the surgical literature with mixed but sometimes promising results, while large-scale evidence specifically for titanium mesh in this application remains limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult male/female patients with age interval 18:60 years old. * Patients with one or more teeth requiring implant supported dental restoration in atrophic maxilla. * Alveolar bone height less than 5 mm at the defective site. * Good oral hygiene. * Patient's consensual agreement to be enrolled in the study. Exclusion Criteria: * Medically compromised patients with conditions contraindicating surgery (eg. uncontrolled diabetics, bisphosphonate intake, radio or chemotherapy). * Patients with active infection at or related to the site of surgery (eg. acute sinusitis). * Heavy smokers. * Patients not indicated for an implant supported restoration at the time of enrollement (eg. active/untreated periodontal disease). (Patients developing any medical condition that interferes with the outcomes after enrolment in the study will be excluded).
Where this trial is running
Ismailia
- Suez Canal University — Ismailia, Egypt (RECRUITING)
Study contacts
- Study coordinator: Hedra Sherif Michael
- Email: Hedra_sherif@dent.suez.edu.eg
- Phone: +201226182970
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Maxillary Sinus Floor Augmentation, Tenting, Schneiderian membrane