Tele-Rehabilitation for Recovery from Mild Traumatic Brain Injury

Tele-Rehabilitation to Improve Mild Traumatic Brain Injury Recovery and Reduce Subsequent Injury Risk

Phase 1 Interventional University of Colorado, Denver · NCT05594225

This study is testing a smartphone-based rehab program to see if it helps military members and young adults recover better from concussions compared to regular care.

Quick facts

PhasePhase 1
Study typeInterventional
Enrollment88 (estimated)
Ages18 Years to 40 Years
SexAll
SponsorUniversity of Colorado, Denver Academic / other
Locations2 sites (Aurora, Colorado and 1 other locations)
Trial IDNCT05594225 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the feasibility and effectiveness of a smartphone-based virtual Neuromuscular/Dual-Task intervention for military service members and active young adults recovering from a recent concussion. The study will assess baseline neuromuscular performance and compare it between military personnel and civilians, while also examining the impact of the intervention on reducing musculoskeletal injuries and improving performance in dual-task scenarios. Participants will be randomized to receive either the virtual intervention or standard care within three weeks of their mild traumatic brain injury.

Who should consider this trial

Good fit: Ideal candidates are active-duty military service members and physically active young adults aged 18-40 who have recently been diagnosed with a mild traumatic brain injury.

Not a fit: Patients with moderate or severe traumatic brain injuries or those with pre-existing neurological disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly enhance recovery outcomes and reduce the risk of further injuries for individuals with mild traumatic brain injuries.

How similar studies have performed: Other studies have shown promise in using virtual rehabilitation approaches for injury recovery, suggesting potential success for this novel intervention.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18-40 years of age at the time of enrollment
* Mild TBI or concussion diagnosis by a physician
* Confirmed MTBI diagnosis via VA/DOD guidelines at time of enrollment
* Participation in regular physical activity prior to injury (confirmed via the Global Physical Activity Questionnaire \[GPAQ\]) (Cleland et al., 2014; Keating et al., 2019)
* Access to a smartphone for app download

Exclusion Criteria:

* Moderate or severe TBI
* Pre-injury neurological disorder
* Abnormal brain imaging findings (if performed as a part of routine care)
* Previous TBI (mild/moderate/severe) \<12 months prior to enrollment other than the current injury for which they are being seen

Where this trial is running

Aurora, Colorado and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Brain Concussion
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.