Techniques to preserve alveolar bone after tooth extraction
Guided Bone Regeneration in Alveolar Socket Using a Synthetic Resorbable Membrane. a Randomized Controlled Trial
NA · Aristotle University Of Thessaloniki · NCT05577663
This study is testing which of three different methods can best help preserve the bone in your jaw after a tooth is pulled.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 39 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Aristotle University Of Thessaloniki (other) |
| Locations | 1 site (Thessaloniki) |
| Trial ID | NCT05577663 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of two different socket seal techniques for preserving alveolar bone following tooth extraction. Participants will be randomly assigned to one of three groups: one receiving standard suturing, another receiving a free gingival graft, and the third using a polylactic-glycolic acid membrane. The primary focus is on measuring changes in alveolar bone height and width, as well as other secondary outcomes related to tissue healing. The goal is to determine which method best stabilizes the blood clot and minimizes bone resorption.
Who should consider this trial
Good fit: Ideal candidates are individuals requiring a single tooth extraction with less than 50% periodontal destruction.
Not a fit: Patients with systemic diseases affecting wound healing or those requiring multiple extractions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved techniques for preserving alveolar bone, enhancing outcomes for dental implant placements.
How similar studies have performed: Previous studies have shown varying degrees of success with similar socket preservation techniques, indicating potential for positive outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Referrals for a single tooth extraction * Periodontal destruction less than 50% of tooth support * Signed inform consent form Exclusion Criteria: * Systematic diseases, contradicting surgical procedures and compromise wound healing (i.e. uncontrolled diabetes) * Medication that interferes with bone metabolism * Pregnancy or lactation * Multiple extractions * Absence of adjacent teeth * Loss of buccal bone, either due to periodontal disease or because of traumatic extraction
Where this trial is running
Thessaloniki
- Dental School, Aristotle University, Dept of Preventive Dentistry, Periodontology and Implant Biology — Thessaloniki, Greece (RECRUITING)
Study contacts
- Study coordinator: Danae Apatzidou, Assoc. Professor
- Email: dapatzidou@dent.auth.gr
- Phone: +306934770361
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Alveolar Bone Resorption, socket seal, randomized controlled clinical trial, alveolar ridge preservation, polylactic-glycolic acid membrane, free gingival graft, spontaneous healing