Task-specific electrical stimulation to improve upper limb gross motor skills in children with spastic quadriplegia
Official title: Effect of Task Specific Electrical Stimulation on Upper Limb Gross Motor Skills in Children With Spastic Quadriplegia
Run by Kafrelsheikh University · NCT06925425 · Data updated 2026-11-12
This trial tests whether task-specific electrical stimulation combined with targeted physical therapy can help improve arm and hand gross motor skills in children aged 2–6 with spastic quadriplegic cerebral palsy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 2 Years to 6 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Kafrelsheikh University Academic / other |
| Locations | 1 site (Alexandria, Egypt) |
| Status | Recruiting |
| Started | May 1, 2025 |
| Main results expected | March 1, 2026 |
| Study ends | March 29, 2026 |
| Registry record updated | April 1, 2026 |
| Trial ID | NCT06925425 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children aged 2–6 years diagnosed with spastic quadriplegic cerebral palsy, with MAS 1+ to 2 spasticity, GMFCS level III–IV, and whose parents can consent and attend all sessions.
✕Probably not a fit
Children with fixed upper-limb deformities, prior upper-limb surgery, severe hearing or visual impairment, or those unable to attend regular sessions are unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an interventional study delivering task-specific electrical stimulation (TASES) alongside a designed physical therapy program to children with spastic quadriplegic cerebral palsy. Eligible children are aged 2–6 years with Modified Ashworth Scale spasticity of 1+ to 2 and GMFCS level III or IV, and must attend in-person treatment and assessment visits. Children with prior upper-limb neurological or orthopedic surgery, fixed joint deformities, or severe hearing or vision loss are excluded. The trial measures changes in upper-limb gross motor skills after a program of repeated, task-focused electrical stimulation and therapy.
Why it matters
Potential benefit: If successful, the approach could improve arm and hand control and daily function for young children with spastic quadriplegia.
How similar studies have gone: Related approaches combining functional or task-focused electrical stimulation with therapy have shown some positive improvements in upper-limb control in children with CP, but evidence specifically in young children with spastic quadriplegia remains limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Their age will be ranged from 2 to 6 years. Their grade of spasticity will be from 1+ to 2 according to Modified Ashworth scale (Baunsgaard etal., 2016). (APPENDIX II). 2. They will be on Level III and IV according to Gross Motor Functional Classification System (GMFCS) (Palisano et al., 2008).(APPENDIX III). 3. Parents/legals representatives consenting to their child's participation 5 - Diagnosed with Spastic Quadriplegic cerebral palsy Exclusion Criteria: 1. Previous neurological or orthopedic surgery in the upperextremities. 2. Fixed deformity in the joints of upper limb. 3- Severe hearing and visual defect. 4-Irregular attendance at assessments or therapy sessions
Where it's running
-
Aalaa Ahmed Farrag
Alexandria, Egypt, Egypt Recruiting
Study contacts
- Principal investigator: Mohamed Bedair Ibrahim, professor of physical therapy — Kafrelsheikh University
- Study coordinator: Mohamed Bedair Ibrahim, Professor of Physical Therapy
- Email: aalaasoliman110@gmail.com
- Phone: +2 01223800014
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.