Takayasu arteritis that affects the lung arteries: symptoms and long-term outlook

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Investigators will prospectively collect and analyze clinical, imaging, and treatment data on patients with Takayasu arteritis and computed tomography–confirmed pulmonary artery involvement admitted to China-Japan Friendship Hospital between January 1, 2016 and December 31, 2026. The work will describe clinical characteristics and current multimodal management patterns and document long-term outcomes. Statistical analyses will explore risk factors for death and factors associated with development of pulmonary hypertension using predefined diagnostic criteria and imaging findings. Patients with other causes of pulmonary artery stenosis or occlusion will be excluded to isolate Takayasu-related involvement.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Hospitalized between Jan 1, 2016 and Dec 31, 2026
* Diagnosed with TAK according to the modified Ishikawa criteria and/or 1990 American College of Rheumatology criteria and/or 2022 ACR/EULAR criteria
* Diagnosed with pulmonary artery involvement using computed tomography pulmonary angiography or transcatheter pulmonary angiography
* Patients without aortic or primary branch involvement who nonetheless exhibited both clinical features and computed tomography-confirmed evidence of pulmonary artery involvement (PAI), after exclusion of other diseases causing pulmonary artery stenosis or occlusion

Exclusion Criteria:

* Patients with PAI caused by non-TAK diseases such as other types of vasculitis, fibrosing mediastinitis, pulmonary artery sarcoma, pulmonary sarcoidosis or chronic thromboembolic pulmonary hypertension

Where it's running

• China-Japan Friendship hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Wanmu Xie, Doctor
• Email: xiewanmu@126.com
• Phone: 15611734410

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  This study is testing if a combination of medication and a special procedure can help people with Takayasu arteritis who have problems with their pulmonary arteries feel better and improve their treatment results.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.