Tailored resistance exercise for older adults

A Tailored Intervention to Prevent Age-Related Declines in Muscle Power and Functional Ability

Not applicable Interventional Universitaire Ziekenhuizen KU Leuven · NCT06449716

This study tests if a personalized resistance exercise program can help older adults aged 65 to 80 maintain their strength and everyday abilities better than a standard exercise routine.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment72 (estimated)
Ages65 Years to 80 Years
SexAll
SponsorUniversitaire Ziekenhuizen KU Leuven Academic / other
Locations1 site (Leuven, Vlaams-Brabant)
Trial IDNCT06449716 on ClinicalTrials.gov

What this trial studies

This study investigates a novel approach to resistance exercise aimed at preserving functional ability in older adults by tailoring exercise doses based on individual force-velocity profiles. The intervention consists of a 12-week progressive power-oriented resistance exercise program designed specifically for community-dwelling adults aged 65 to 80. Participants will be randomly assigned to either the tailored exercise group or a traditional resistance exercise group to assess the effectiveness of this individualized approach. The goal is to determine if personalized training can lead to better outcomes in muscle power and functional ability compared to standard methods.

Who should consider this trial

Good fit: Ideal candidates for this study are community-dwelling adults aged 65 to 80 who have not engaged in systematic resistance exercise in the past year.

Not a fit: Patients with unstable cardiovascular or neuromuscular diseases, recent surgeries, or low functional ability may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly enhance the functional ability and quality of life for older adults by improving muscle power.

How similar studies have performed: While traditional resistance training has been effective for many, this tailored approach is novel and has not been extensively tested in previous studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Community-dwelling adults
* 65-80 years old

Exclusion Criteria:

* Systematic engagement in resistance exercise during the past year
* Unstable cardiovascular disease, neuromuscular disease, acute infection or fever
* Recent surgery
* Lower-extremity injuries
* Low levels of functional ability (i.e., SPPB score ≤ 9)
* Cognitive malfunctioning (i.e., Mini-Mental State Examination \< 24)

Where this trial is running

Leuven, Vlaams-Brabant

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Exercise Training
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.