Tailored neuropsychological profile in Sturge-Weber Syndrome
Official title: Exploring the Neuropsychological Profile of Sturge-Weber Syndrome for Developing Tailored Rehabilitation.
Run by University of Roma La Sapienza · NCT07655492 · Data updated 2026-11-12
This observational study tests the neuropsychological profile of people with Sturge-Weber Syndrome to understand cognitive strengths and weaknesses across ages.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 2 Years and up |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | University of Roma La Sapienza Academic / other |
| Locations | 1 site (Roma, Roma) |
| Status | Recruiting |
| Started | June 10, 2026 |
| Main results expected | July 1, 2026 |
| Study ends | November 1, 2026 |
| Registry record updated | June 17, 2026 |
| Trial ID | NCT07655492 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Individuals with confirmed Sturge-Weber Syndrome, aged 2 years or older, able to cooperate with neuropsychological testing.
✕Probably not a fit
Patients unable to participate in neuropsychological testing or those outside the age range may not benefit from the study results directly.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study seeks to characterize the neuropsychological profile of individuals with Sturge-Weber Syndrome, from children to adults. Researchers will examine visuospatial abilities, working memory, and executive functions, and compare cognitive phenotypes between those with and without the facial port-wine stain. The study will consider how clinical factors like seizure history and brain involvement relate to cognitive performance. Participants must be 2 years or older and able to cooperate with testing. No intervention is being tested; the aim is to describe cognition and relationships to clinical features.
Why it matters
Potential benefit: Findings could improve understanding of cognitive challenges in SWS and inform future personalized rehabilitation strategies.
How similar studies have gone: Prior research using neuropsychological methods in SWS has helped map cognitive profiles, supporting the value of this observational approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Confirmed diagnosis of Sturge-Weber Syndrome (SWS) of any type (Type I, Type II, or Type III) based on clinical and/or neuroimaging findings * Age 2 years or older at the time of enrollment (children, adolescents, and adults are eligible) * Ability to cooperate with neuropsychological testing procedures * Willingness to complete all study assessments within the designated timeframe Exclusion Criteria: * Absence of confirmed Sturge-Weber Syndrome (SWS) * Age younger than 2 years at the time of enrollment * Inability to cooperate with neuropsychological testing procedures even with accommodations or modifications
Where it's running
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Department of Psychology University of Rome
Roma, Roma, Italy Recruiting
Study contacts
- Principal investigator: Laura Piccardi, PhD — University of Roma La Sapienza
- Study coordinator: Laura Piccardi, PhD
- Email: laura.piccardi@uniroma1.it
- Phone: +39 06 49917527
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Presymptomatic Epidiolex for Sturge-Weber Syndrome
This study tests whether cannabidiol (Epidiolex) started in babies with Sturge-Weber syndrome can delay the first seizure.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.