Tailored hydration using ReDS lung‑water monitoring to prevent kidney injury during coronary angiography and intervention

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Elderly patients with coronary disease often have chronic kidney disease and are at risk for contrast‑induced acute kidney injury (CI‑AKI) after percutaneous coronary intervention. This randomized interventional study compares tailored hydration guided by the Remote Dielectric Sensing (ReDS) lung‑water index versus standard hydration in patients scheduled for coronary intervention. The ReDS device is used to dynamically monitor lung water and adjust infusion rates to avoid fluid overload and acute pulmonary edema while providing necessary hydration. Outcomes include perioperative CI‑AKI, acute pulmonary edema, and longer‑term major cardiovascular events and need for hemodialysis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 60 years;
* Patients with unstable angina pectoris are scheduled for percutaneous coronary intervention；
* Patients with chronic renal disease (estimated glomerular filtration rate \< 90 ml/min);
* Sign the informed consent form.

Exclusion Criteria:

* 1\. Acute decompensated severe heart failure or cardiogenic shock;
* 2\. Malignant tumors, severe renal failure (estimated glomerular filtration rate \< 30 ml/min);
* 3\. Respiratory failure;
* 4\. Used contrast media within one week;
* 5\. Have allergic to contrast medium

Where it's running

• Chinese PLA general hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Geng Qian, MD
• Email: qiangeng9396@263.net
• Phone: 086-010-55499209

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Managing multiple medications in older adults with chronic diseases

  This project will see if taking many different medicines changes the health outlook of people aged 65 and older who have chronic conditions.

  Recruiting Xijing Hospital · Xi'an, Shaanxi · NCT07180368

• My Heart and CKD: A Shared Decision Aid to Help CKD and CAD Patients Choose Heart Procedures

  A patient-focused online tool tests whether a personalized decision aid can help adults with chronic kidney disease and coronary artery disease make informed choices about heart procedures.

  Recruiting at 2 sites University of Calgary · Calgary, Alberta and 1 other locations · NCT06920927

• Observational look at how Kremezin works in adults with advanced chronic kidney disease

  This study tests whether Kremezin helps adults with advanced kidney disease when used as part of routine care, by tracking safety and kidney function over up to 48 weeks.

  Recruiting HK inno.N Corporation · Seoul · NCT07930169

• μFR-guided Drug-Coated Balloon Angioplasty vs Angiography-guided Angioplasty in Coronary Artery Disease

  This trial tests whether using computational μFR guidance during drug-coated balloon angioplasty is better than standard angiography guidance for people with de novo coronary artery lesions.

  Recruiting Centro Cardiologico Monzino · Cosenza, CS and 3 other locations · NCT07917234

• Kidney and Heart Health in Adults with Type 2 Diabetes and CKD Treated with Semaglutide in China

  This study tests whether semaglutide injections help kidney and heart health in adults with type 2 diabetes and chronic kidney disease.

  Recruiting Phase 4 Novo Nordisk A/S · Fuyang, Anhui and 25 other locations · NCT07900438

• Gastric Ultrasound Before CABG to See if Heart Function Changes Stomach Contents

  This study checks whether people with weaker heart function before elective CABG have different stomach contents seen on ultrasound.

  Recruiting Adiyaman University · Adıyaman · NCT07898215

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.