Switching a DPP‑4 drug to a TZD for adults on metformin plus an SGLT2 inhibitor

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, open-label, active-controlled, parallel, multicenter Phase IV trial comparing continued metformin + SGLT2 inhibitor + DPP‑4 inhibitor versus switching the DPP‑4 inhibitor to a TZD in adults with type 2 diabetes. Participants will be allocated to treatment groups and followed for measures of glycemic control and safety events. The main goals are to compare efficacy (for example, blood glucose control) and adverse effects between the two combination regimens. Standard clinical monitoring and laboratory tests will be used to detect benefits and harms.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Has voluntarily agreed to participate in this clinical trial.
* Adults over 19 years of age
* Diagnosed with type 2 diabetes

Exclusion Criteria:

* Has severe renal and liver disorders
* Has type 1 diabetes
* Those who are participating or have participated in other clinical trials and administered their investigational products within 8 weeks before the screening date for this study
* Those who are deemed ineligible to participate in the study by the investigator

Where it's running

• The Catholic University of Korea, Seoul St. Mary's Hospital
  Seoul, Seocho District, South Korea Recruiting

Study contacts

• Study coordinator: Oh
• Email: syoh@boryung.co.kr
• Phone: +82 2-708-8000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.