SwissNeuroRehab HDHI — High-Dose, High-Intensity Stroke Rehabilitation Program

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a multicentre, non-randomised interventional feasibility project run within the SwissNeuroRehab network that implements a structured high-dose, high-intensity (HDHI) therapy pathway using CE‑marked digital neurorehabilitation tools. The pathway is designed for delivery across inpatient, outpatient, and home environments at several Swiss rehabilitation centres. Adults with ischemic or hemorrhagic stroke who can sit unassisted and have upper and/or lower limb motor difficulties are enrolled and asked to commit to a daily training dose and program length. Feasibility measures and preliminary clinical outcomes are collected at the start and end of the program to inform wider implementation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18-85 years.
* Confirmed diagnosis of stroke (ischemic or hemorrhagic) \>7 days ago
* Be able to sit unassisted
* Able and willing to give informed consent
* Have motor difficulties of the Upper Extremity and/or Lower Extremity
* Willing to commit to program length \& daily training dose
* Willing to have assessments at start and end of program
* Signed informed consent

Exclusion Criteria:

* Severe cognitive impairment
* Uncontrolled seizure disorder or epilepsy - clinician's judgement)
* Any medical condition that would compromise their safety (inability to communicate, vision or hearing impairment, heart condition that limits participation in exercise) and tolerability (cardiac contraindications)
* Pain that would limit rehabilitation dose
* Severe apraxia
* Severe memory disorder
* Severe hemispatial neglect
* Plegia of the affected limb

Where it's running

• Klinik Valens
  Valens, Canton of St. Gallen, Switzerland Recruiting
• Centre hospitalier universitaire Vaudois
  Lausanne, Canton of Vaud, Switzerland Recruiting
• Swiss Réhabilitation Sàrl
  Sullens, Canton of Vaud, Switzerland Recruiting
• Lake Lucerne Institute
  Vitznau, Canton of Lucerne, Switzerland Not yet recruiting
• Universitätspital Zürich
  Zurich, Canton of Zurich, Switzerland Not yet recruiting

Study contacts

• Study coordinator: Olivier Bill, MD
• Email: olivier.bill@chuv.ch
• Phone: +41 0213141260

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Web-based therapy using action observation and mirror therapy for arm weakness after stroke

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• Remote Ischaemic Conditioning for Fatigue After Stroke 2

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• Dual-task balance training plus computer-based cognitive training after stroke

  In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.

  Recruiting Matia Foundation · San Sebastián, GUIPUZCOA · NCT07913620

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.