Sustaining and tailoring school-based HIV prevention
Official title: National Implementation of an Evidence-Based HIV Prevention Program: Multilevel Scale-Up Strategies and Precision Prevention
Run by University of Massachusetts, Worcester · NCT07153042 · Data updated 2026-11-12
This project will test adaptive support strategies and machine learning to help Bahamian teachers keep an evidence-based HIV prevention curriculum working well for grade 6–9 students and their teachers.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 10 Years to 60 Years |
| Sex | All |
| Enrollment | 3705 (estimated) |
| Sponsor | University of Massachusetts, Worcester Academic / other |
| Locations | 1 site (Nassau) |
| Status | Recruiting |
| Started | October 1, 2025 |
| Main results expected | August 31, 2029 |
| Study ends | November 30, 2029 |
| Registry record updated | September 24, 2026 |
| Trial ID | NCT07153042 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are grade 6 students (followed through grades 7–9) and Health and Family Life Education teachers at the participating government primary and junior high schools in the Bahamas who speak and read English.
✕Probably not a fit
Students who opt out, who cannot read or speak English sufficiently, or who are already in classrooms delivering the full curriculum with high fidelity may not receive additional benefit from the adaptive strategies.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This five-year hybrid type 3 implementation project uses a SMART (Sequential, Multiple Assignment, Randomized Trial) design to compare multilevel strategies—like biweekly monitoring, site-based mentorship, and enhanced mentorship—for sustaining the FOYC+CImPACT HIV prevention curriculum in schools. The trial enrolls grade 6 teachers and students in 65 government primary schools and HFLE teachers and classes in 30 junior high schools across multiple Bahamian islands. Advanced machine learning methods will be used iteratively to identify teachers who deliver less than 80% of core activities and students unlikely to respond, and to tailor implementation strategies accordingly. Primary outcomes are program sustainability and continued effectiveness measured via teacher, student, and contextual data over four years of follow-up.
Why it matters
Potential benefit: If successful, schools could maintain higher-quality HIV prevention lessons over time, which may reduce adolescent HIV risk behaviors and improve long-term program reach.
How similar studies have gone: The FOYC+CImPACT curriculum has prior evidence of effectiveness in Caribbean settings, while applying SMART adaptive designs combined with machine learning to boost long-term sustainability is a newer and less-tested approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Grade 6 teachers who teach Health and Family Life Education (HFLE) and their classes in 65 government primary schools. * Grade 7-9 HFLE teachers and their classes in 30 middle schools across 12 Bahamian islands. * FOYC (Focus on Youth in the Caribbean) is delivered as part of the standard HFLE curriculum. * Students who: 1) are enrolled in one of the participating schools as general education students in grade 6 (and followed through grades 7-9); and 2) speak and read English. Exclusion Criteria: * Students who chose to opt out of participating in the study * Students who do not speak or read English sufficiently to participate in study activities.
Where it's running
-
HIV/AIDS Office, FOY program
Nassau, The Bahamas Recruiting
Study contacts
- Principal investigator: Bo Wang, PhD — UMass Chan Medical School
- Study coordinator: Lynette Deveaux
- Email: lyndeveaux@yahoo.com
- Phone: 1-242-454-8488
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.