Survey on the use of REXULTI for managing aggressive behavior in Alzheimer's patients

REXULTI Drug General Use-results Survey (Excessive Motor Activity or Physically/Verbally Aggressive Behavior Due to Rapid Changes in Mood, Irritability, and/or Outbursts Associated With Dementia Due to Alzheimer's Disease)

Observational Otsuka Pharmaceutical Co., Ltd. · NCT06875986

This study is testing if REXULTI can help manage aggressive behavior in people with Alzheimer's disease by looking at how well it works and its safety in everyday settings.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages15 Years and up
SexAll
SponsorOtsuka Pharmaceutical Co., Ltd. Industry-sponsored
Locations1 site (Osaka, Osaka)
Trial IDNCT06875986 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the safety and efficacy of REXULTI (brexpiprazole) in patients diagnosed with Alzheimer's disease who exhibit excessive motor activity or aggressive behavior due to mood changes. The study will collect data from daily clinical settings to assess how well the medication performs in real-world scenarios. By monitoring patient responses and side effects, the study seeks to provide valuable insights into the drug's effectiveness for managing symptoms associated with Alzheimer's.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with Alzheimer's disease who display excessive motor activity or aggressive behavior.

Not a fit: Patients who do not have a diagnosis of Alzheimer's disease or do not exhibit aggressive behaviors may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the management of aggressive behaviors in Alzheimer's patients, enhancing their quality of life.

How similar studies have performed: While this approach is observational, similar studies evaluating the efficacy of medications like REXULTI in managing behavioral symptoms in dementia have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients diagnosed with Alzheimer's disease

Exclusion Criteria:

\-

Where this trial is running

Osaka, Osaka

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Alzheimer Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.