Clinical trial Recruiting at 1 site Observational Ages 15 and up

Survey on the use of REXULTI for managing aggressive behavior in Alzheimer's patients

Official title: REXULTI Drug General Use-results Survey (Excessive Motor Activity or Physically/Verbally Aggressive Behavior Due to Rapid Changes in Mood, Irritability, and/or Outbursts Associated With Dementia Due to Alzheimer's Disease)

Run by Otsuka Pharmaceutical Co., Ltd. · NCT06875986 · Data updated 2026-11-12

This study is testing if REXULTI can help manage aggressive behavior in people with Alzheimer's disease by looking at how well it works and its safety in everyday settings.

More Alzheimer Disease trials

Quick facts

Study typeObservational
Ages15 Years and up
SexAll
Enrollment200 (estimated)
SponsorOtsuka Pharmaceutical Co., Ltd.
Industry-sponsored
Locations1 site (Osaka)
StatusRecruiting
StartedApril 17, 2025
Main results expectedSeptember 30, 2027
Study endsSeptember 23, 2028
Registry record updatedOctober 20, 2026
Trial IDNCT06875986 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients diagnosed with Alzheimer's disease who display excessive motor activity or aggressive behavior.

Probably not a fit

Patients who do not have a diagnosis of Alzheimer's disease or do not exhibit aggressive behaviors may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the safety and efficacy of REXULTI (brexpiprazole) in patients diagnosed with Alzheimer's disease who exhibit excessive motor activity or aggressive behavior due to mood changes. The study will collect data from daily clinical settings to assess how well the medication performs in real-world scenarios. By monitoring patient responses and side effects, the study seeks to provide valuable insights into the drug's effectiveness for managing symptoms associated with Alzheimer's.

Why it matters

Potential benefit: If successful, this study could improve the management of aggressive behaviors in Alzheimer's patients, enhancing their quality of life.

How similar studies have gone: While this approach is observational, similar studies evaluating the efficacy of medications like REXULTI in managing behavioral symptoms in dementia have shown promising results.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients diagnosed with Alzheimer's disease

Exclusion Criteria:

\-

Where it's running

  • Pharmacovigilance Department
    Osaka, Japan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.