Survey on perioperative hypersensitivity reactions
Epidemiological Survey on Perioperative Hypersensitivity Reactions in France by the GERAP Network (Groupe d'étude Des réactions Anaphylactiques périopératoires)
University Hospital, Strasbourg, France · NCT04654923
This study looks at how often people have allergic reactions during surgery over the last 10 years to help make surgeries safer for patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3000 (estimated) |
| Ages | 7 Years and up |
| Sex | All |
| Sponsor | University Hospital, Strasbourg, France (other) |
| Locations | 1 site (Strasbourg) |
| Trial ID | NCT04654923 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the epidemiology of perioperative hypersensitivity reactions over a 10-year period. It will analyze patient and reaction phenotypes, as well as the outcomes of allergic work-ups for individuals who have experienced such reactions. The study will collect data from patients referred for evaluation after experiencing hypersensitivity reactions during surgery. By understanding these reactions better, the study seeks to improve patient safety and management in perioperative settings.
Who should consider this trial
Good fit: Ideal candidates include individuals who have experienced a perioperative hypersensitivity reaction between January 1, 2017, and December 31, 2027, and are referred for an allergic work-up.
Not a fit: Patients who have not experienced a perioperative hypersensitivity reaction or those who oppose the reuse of their data for research purposes may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding and management of perioperative hypersensitivity reactions, potentially reducing morbidity and mortality associated with these events.
How similar studies have performed: While the specific approach of this study may be novel, previous studies have indicated the importance of understanding the epidemiology of hypersensitivity reactions in improving clinical outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Minor and major subject * Subject having experienced a perioperative hypersensitivity reaction between January the 1st 2017 and December the 31st 2027. * Referred for an allegro-anesthetic workup * Subject not having expressed his opposition, after information, to the reuse of his data for the purposes of this research. Exclusion Criteria: * Subject having expressed opposition to participating in the study * Inability to provide the subject with research information * Subject under guardianship or guardianship * Subject under safeguard of justice
Where this trial is running
Strasbourg
- Service d'anesthésie-réanimation - CHU de Strasbourg - France — Strasbourg, France (RECRUITING)
Study contacts
- Principal investigator: Charles TACQUARD, MD — Strasbourg University Hospitals - Anesthesia-intensive care unit
- Study coordinator: Paul-Michel MERTES, MD, PhD
- Email: paul-michel.mertes@chru-strasbourg.fr
- Phone: 33 3 69 55 04 44
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Hypersensitivity, Drug, anaphylaxis, perioperative, hypersensitivity reactions, neuromuscular blocking agents, hypnotics