Surgical treatment for women with deep endometriosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The TrEnd trial collects data from women undergoing segmental sigmoid colon or rectal resection due to deep endometriosis. This observational study aims to compile a large series of cases treated with standardized surgical techniques to evaluate complications and long-term outcomes. By analyzing these cases, the study seeks to improve understanding of surgical interventions for this condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age \>/= 18 years;
* presence of deep endometriotic nodule(s) infiltrating the tunica muscularis of the sigmoid colon/rectum.

Exclusion Criteria:

* age \<18 years:
* presence of coexisting inflammatory bowel disease;
* patients who have received previous pelvic radiotherapy.

Where it's running

• Casa Di Cura Malzoni Villa Platani Spa
  Avellino, Campania, Italy Recruiting

Study contacts

• Principal investigator: Mario Malzoni, MD — malzonimario@gmail.com
• Study coordinator: Mario Malzoni, MD
• Email: malzonimario@gmail.com
• Phone: 0825796111

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• 3D Modeling of Deep Endometriosis From Pelvic MRI

  Acknowledge how 3D reconstructions from pelvic MRI are tested to see if they help plan surgeries for people with deep endometriosis.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT07864883

• Franco-European Institute of Endometriosis long-term outcomes cohort

  This cohort will follow women with confirmed pelvic endometriosis to see if different medical and surgical treatments lead to better long-term symptoms, quality of life, recurrence rates, and fertility outcomes.

  Recruiting Clinique Tivoli Ducos · Bordeaux · NCT07243587

• Identifying ureters during deep endometriosis surgery using indocyanine green dye instead of ureteric stents

  This project will see if injecting indocyanine green dye into the ureters causes less postoperative pain than placing ureteric stents for women aged 18–50 undergoing laparoscopic or robotic surgery for deep endometriosis.

  Recruiting University Hospitals of North Midlands NHS Trust · Stoke-on-Trent, Staffordshire · NCT06852248

• Evaluating MRI Techniques for Diagnosing Deep Endometriosis

  This study is testing new MRI techniques to see if they can help doctors better plan surgery for young women with deep endometriosis.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, Bologna · NCT06799767

• Comparing robotic and laparoscopic surgery for deep endometriosis

  This study is testing whether robot-assisted surgery is better than regular laparoscopic surgery for people with deep endometriosis in terms of pain relief and quality of life after the procedure.

  Recruiting University of Oulu · Oulu · NCT05179109

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.