Surgical treatment for recurrent neurogenic thoracic outlet syndrome using free fat flaps

Prospective Evaluation of Improvement in Pain and Quality of Life After Free Fat Flap for Treatment of Recurrent Neurological Thoracobrachial Outlet Syndrome

Nantes University Hospital · NCT06172101

This study tests whether using free fat flaps during surgery can help people with recurrent neurogenic thoracic outlet syndrome feel better and prevent their symptoms from coming back.

Quick facts

Study typeObservational
Enrollment20 (estimated)
Ages18 Years and up
SexAll
SponsorNantes University Hospital (other)
Locations1 site (Nantes)
Trial IDNCT06172101 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of using free fat flaps to cover the neurolyzed brachial plexus in patients with recurrent neurogenic thoracic outlet syndrome. The goal is to improve local vascularization and reduce the risk of symptom recurrence after surgical intervention. Participants will be assessed using validated questionnaires to evaluate the impact of this surgical approach. The study focuses on patients who have previously undergone brachial plexus neurolysis and are experiencing recurrent symptoms.

Who should consider this trial

Good fit: Ideal candidates are patients who have undergone brachial plexus neurolysis and are experiencing recurrent symptoms of thoracic outlet syndrome.

Not a fit: Patients who are unable to provide consent or have language barriers may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce the recurrence of symptoms in patients with neurogenic thoracic outlet syndrome.

How similar studies have performed: While the use of fat flaps in surgical procedures is established, this specific application in recurrent neurogenic thoracic outlet syndrome is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients underwent brachial plexus neurolysis and free fat flap coverage in the context of recurrence of neurological thoraco-brachial outlet syndrome

Exclusion Criteria:

* Patients were unable to express their non-opposition to participating in the study.
* patients under guardianship or trusteeship.
* patients whose mother tongue is not French.
* patients who cannot read and/or write.

Where this trial is running

Nantes

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Neurogenic Thoracic Outlet Syndrome, Recurrent neurogenic thoracic outlet syndrome, Free fat flap

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.