Surgical treatment for chronic rhinosinusitis
A Prospective Single-center Cohort Study of Surgical Treatment of Chronic Rhinosinusitis
This study is testing whether surgery can help people with chronic rhinosinusitis feel better and improve their quality of life when other treatments haven't worked.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Sex | All |
| Sponsor | Beijing Tongren Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing) |
| Trial ID | NCT06010316 on ClinicalTrials.gov |
What this trial studies
This study focuses on patients diagnosed with chronic rhinosinusitis (CRS), a condition characterized by prolonged nasal congestion, runny nose, and decreased sense of smell. It aims to observe the outcomes of surgical interventions in patients who have not responded well to conservative treatments. The study will collect data on patient symptoms and quality of life before and after surgery to evaluate the effectiveness of the surgical approach. The research will follow patients over time to assess long-term benefits and complications associated with the surgical treatment.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with chronic rhinosinusitis who have not found relief from conservative treatments and are indicated for surgery.
Not a fit: Patients with co-existing conditions that may interfere with the evaluation of surgical efficacy or those with certain nasal cavity tumors will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly improve the quality of life for patients suffering from chronic rhinosinusitis by providing effective surgical options.
How similar studies have performed: Other studies have shown promising results with surgical interventions for chronic rhinosinusitis, indicating that this approach is supported by existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * (1) Meeting the CRS diagnostic criteria in the Chinese Guidelines for the Diagnosis and Treatment of Chronic Sinusitis (2018); (2) The effect of conservative drug treatment is not good or there are indications of surgery; (3) Good compliance, able to complete clinical observation. Compliance with guidelines Exclusion Criteria: * (1) The patient has conditions or co-existing diseases that may preclude the primary efficacy endpoint evaluation, such as benign or malignant tumors of the nasal cavity; (2) Clinically significant co-existing diseases that may interfere with clinical efficacy results, including but not limited to: Cystic fibrosis, eosinophilic granuloma with polyvasculitis (Churg-Strauss syndrome), granuloma with polyvasculitis (Wegener's granuloma), Young's synthesis, tuberculosis or other pathogen infection, malignancy, etc. (3) The patient had other medical or non-medical conditions that the investigator considered unsuitable for participation in the study.
Where this trial is running
Beijing, Beijing
- Beijing Tongren Hospital — Beijing, Beijing, China (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.