Surgical outcomes and quality of life after removal of juxtamedullary spinal tumors
Official title: Multicenter Trial on Surgical Outcome and Quality of Life in Juxta-medullary Tumors
Run by University Hospital Muenster · NCT07056023 · Data updated 2026-11-12
This project will collect information from adults with juxtamedullary (intradural, extramedullary) spinal tumors to see which surgical approaches and perioperative practices are linked to better recovery, function, and quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | University Hospital Muenster Academic / other |
| Locations | 1 site (Münster, Nordrhien Westfalen) |
| Status | Recruiting |
| Started | May 1, 2025 |
| Main results expected | June 2027 |
| Study ends | December 2027 |
| Registry record updated | July 9, 2025 |
| Trial ID | NCT07056023 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (age ≥18) with intraspinal, extramedullary juxtamedullary tumors undergoing surgical treatment who can provide informed consent are the intended participants.
✕Probably not a fit
Patients with primary bone tumors invading the spine, vertebral metastases, or those unable to provide informed consent are excluded and are unlikely to benefit from this registry's findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a multicenter, observational registry led by University Hospital Muenster collecting clinical, surgical, and patient-reported outcome data after resection of juxtamedullary spinal tumors (eg, spinal meningioma, schwannoma, ependymoma). Primary measures include extent of resection, neurological function (McCormick scale), and quality of life; secondary analyses will use regression to examine the influence of surgical approach, intraoperative monitoring, bed rest, and laminectomy on outcomes and cerebrospinal fluid leakage. The registry will compare outcomes in patients with mild versus severe preoperative deficits and explore risk factors for incomplete resection and recurrence. Adult patients able to give informed consent and treated at participating centers are eligible; patients with primary bone tumors or vertebral metastases are excluded.
Why it matters
Potential benefit: If successful, the registry could identify surgical techniques and care practices that improve neurological recovery, reduce recurrence risk, and enhance postoperative quality of life for patients with these tumors.
How similar studies have gone: Single-center case series have shown that gross total resection is associated with better outcomes, but large multicenter registries focusing on juxtamedullary tumors are limited, so this approach is relatively novel at scale.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult, age ≥18 years, patients treated on intraspinal, extra medullary tumor * Patients must have sufficient cognitive and language skills to give informed consent Exclusion Criteria: * Absence of informed consent * Lack of ability to consent * Primary bone tumors invading the intra-spinal space * Vertebral metastasis
Where it's running
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University Hospital Muenster
Münster, Nordrhien Westfalen, Germany Recruiting
Study contacts
- Study coordinator: Michael Schwake, MD
- Email: schwakem@uni-muenster.de
- Phone: +49 251 8343930
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.