Surgical fixation for hip fractures in patients on blood thinners

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines patients with intertrochanteric hip fractures who are receiving direct oral anticoagulation (DOAC) therapy and undergo early surgical fixation within 24 hours of injury. The primary goal is to evaluate the reduction in perioperative blood loss associated with early fixation. Additionally, the study aims to assess the impact of early surgical intervention on 30-day and 1-year mortality rates compared to a control group that received delayed fixation. The cohort will be compared to a matched group of patients who had delayed surgery from 2014 to 2018.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Prospective cohort study:

Patients with intertrochanteric fractures that need a surgical fixation and under treatment with a DOAC medication

Control group:

Patients with intertrochanteric fractures under DOAC medication with a delayed surgical fixation from January 2014 to December 2018 (≥ 48 hours after the trauma)

Exclusion Criteria:

Prospective cohort group:

* patients with multiple fractures
* acute heart failure, kidney and lung failure and
* other concomitant diseases which prevent prompt fixation

Retrospective cohort group:

Patients with delayed surgical fixation due to other causes than DOAC medication (e.g. multimorbidity, acute myocardial infarction, acute heart, lung or kidney failure)

Where it's running

• Medical University of Vienna, Department of Traumatology
  Vienna, Austria Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.