Surgery using a single port for lung cancer treatment

Randomized Controlled Trial of the Comparison of Uniport VATS and Non- Uniport VATS for Lung Cancer

NA · The Second Hospital of Shandong University · NCT04212481

This study is testing if a new type of lung cancer surgery that uses just one small opening can help patients recover faster and feel less pain compared to the usual method that uses multiple openings.

Quick facts

PhaseNA
Study typeInterventional
Enrollment300 (estimated)
Ages25 Years to 80 Years
SexAll
SponsorThe Second Hospital of Shandong University (other)
Locations1 site (Jinan, Shandong)
Trial IDNCT04212481 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of uniport video-assisted thoracoscopic surgery (VATS) compared to traditional multi-port VATS for patients with non-small cell lung cancer (NSCLC). The study focuses on various outcomes including operation time, blood loss, postoperative pain, hospital stay duration, and complications. By utilizing fewer ports, the trial aims to reduce postoperative pain and improve recovery times. Participants will be randomly assigned to different surgical approaches to assess the benefits and risks associated with each method.

Who should consider this trial

Good fit: Ideal candidates are patients with early-stage non-small cell lung cancer who have good cardiopulmonary function and are prepared for radical resection.

Not a fit: Patients with advanced-stage lung cancer or poor cardiopulmonary function may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to less postoperative pain and shorter hospital stays for lung cancer patients.

How similar studies have performed: Similar studies have shown promising results with uniport VATS, indicating potential benefits over traditional multi-port techniques.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

patients with cT1-3N0-1M0 NSCLC; good cardiopulmonary function; prepared to undergo radical resection;

Exclusion Criteria:

patients with N3 or M1 NSCLC; poor cardiopulmonary function; not be prepared to undergo radical resection;

Where this trial is running

Jinan, Shandong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Single-port Video-assisted Thoracoscopic Surgery, Non Small Cell Lung Cancer, Perioperative Efficacy, multi-port

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.