Surgery to remove synovium in the quadriceps tendon to reduce knee crepitus after total knee replacement

Partial Synovectomy in Articular Side of Quadriceps Tendon Reduces Crepitus After Posterior Stabilized Total Knee Arthroplasty : a Randomized, Controlled Trial

Not applicable Interventional Gangnam Severance Hospital · NCT06129214

This study is testing if removing a part of the tissue around the quadriceps tendon can help reduce the annoying popping or crackling sound in the knee after total knee replacement surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment78 (estimated)
Ages19 Years and up
SexAll
SponsorGangnam Severance Hospital Academic / other
Locations1 site (Seoul, GangnamGu)
Trial IDNCT06129214 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of partial synovectomy in the distal quadriceps tendon to reduce crepitus in patients undergoing total knee arthroplasty. Participants will be randomly assigned to either an experimental group, which will undergo synovium removal, or a control group, which will not. The study will measure crepitus levels at 3 months, 6 months, and 1 year post-surgery using various scoring systems. Radiologic and physiological evaluations will be conducted prior to surgery to ensure comparability between the two groups.

Who should consider this trial

Good fit: Ideal candidates for this study are patients scheduled for total knee arthroplasty who do not require patella resurfacing.

Not a fit: Patients with significant radiological or physiological variance between knees or those who experience unexpected complications may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve patient satisfaction and outcomes following total knee arthroplasty by reducing crepitus.

How similar studies have performed: While similar approaches have been explored, this specific randomized trial design focusing on synovium removal in the quadriceps tendon is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1.Patients who scheduled to perform both total knee arthroplasty(TKA) using posteiror crucitate sustain type (PS)

Exclusion Criteria:

1. Lost follow up (Including death of patient)
2. Unexpected complication (e.g) Infection, periprosthetic fracture)
3. Patella resurfacing
4. Canceled surgical treatment
5. Refused to enrolled study
6. Too much radiological or physicological variance shown between either knee

Where this trial is running

Seoul, GangnamGu

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Osteoarthritis, KneeRheumatoid Arthritis, KneeSpontaneous Osteonecrosis of Knee
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.