Surgery for spinal cord metastases
Microsurgical Resection of Intramedullary Spinal Cord Metastases - a Retrospective International Multicenter Study
This study is testing whether surgery for spinal cord tumors helps patients recover better and live longer compared to those who only receive radiation or chemotherapy.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Cantonal Hospital of St. Gallen Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Sankt Gallen) |
| Trial ID | NCT06042946 on ClinicalTrials.gov |
What this trial studies
This study aims to create a multi-center, retrospective database to analyze the functional outcomes of patients with intramedullary spinal cord metastases (ISCM) who have undergone surgical treatment. It will compare these outcomes to a control group of patients treated non-operatively with radiotherapy and/or chemotherapy. The primary focus is on assessing the functional status at 90 days post-treatment, while also evaluating pre- and postoperative neurological deficits and overall survival rates. The study seeks to determine if surgical intervention leads to better outcomes without increasing morbidity or mortality.
Who should consider this trial
Good fit: Ideal candidates for this study are adult patients diagnosed with intramedullary spinal cord metastases who are treated at participating centers.
Not a fit: Patients under the age of 18 will not benefit from this study as they are excluded from participation.
Why it matters
Potential benefit: If successful, this study could provide evidence supporting the safety and efficacy of surgical treatment for patients with spinal cord metastases.
How similar studies have performed: While there have been studies on spinal cord metastases, this specific approach of comparing surgical and non-surgical outcomes in a multi-center database is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients admitted to one of the participating centres and treated for ISCM * Available documentation of admission and postoperative status Exclusion Criteria: \- Patients under the age of 18
Where this trial is running
Sankt Gallen
- Cantonal Hospital St. Gallen, Neurosurgery — Sankt Gallen, Switzerland (Recruiting)
Study contacts
- Principal investigator: Martin N. Stienen, PD, MD — Cantonal Hospital of St. Gallen
- Study coordinator: Martin N. Stienen, PD, MD
- Email: martin.stienen@kssg.ch
- Phone: +41 71 494 2183
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.