Surgery for patients with drug-resistant epilepsy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to collect data on patients with drug-resistant epilepsy who undergo standard surgical treatments. It focuses on individuals aged 8 and older whose seizures have not responded to medication. Participants will be screened by neurologists to confirm their diagnosis and may undergo various surgical procedures to remove or modify the epileptic focus. The goal is to better understand epilepsy and its treatment through the data collected during routine care.

Why it matters

Who can join: the full rules

* INCLUSION CRITERIA:

To be eligible for entry into the study, candidates must:

1\. Be 8 years of age or older with drug resistant epilepsy or tumor related epilepsy.

EXCLUSION CRITERIA:

Candidates will be excluded if they:

1\. Are unable or unwilling to give informed consent, or have a parent able to provide informed consent if a minor, to the research procedures.

Where it's running

• National Institutes of Health Clinical Center
  Bethesda, Maryland, United States Recruiting

Study contacts

• Principal investigator: Kareem A Zaghloul, M.D. — National Institute of Neurological Disorders and Stroke (NINDS)
• Study coordinator: Surgical Neurology Branch
• Email: nindsdir-snbrecruiti@ninds.nih.gov
• Phone: (301) 496-2921

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Investigating epilepsy and its treatment options

  This study is looking to better understand epilepsy and improve treatments for people aged 8 and older who have drug-resistant epilepsy by examining their medical history and conducting tests.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT03478852

• Evaluating a new ultrasound treatment for drug-resistant epilepsy

  This study is testing a new ultrasound treatment for people with drug-resistant epilepsy to see if it can help reduce their seizures and improve their quality of life.

  Recruiting NaviFUS Corporation · Taipei · NCT06492720

• Mapping Epileptic Networks with MRI and iEEG

  This study is testing a new way to use MRI and brain wave recordings to help people with hard-to-treat epilepsy understand their seizures better and improve their chances of successful surgery.

  Recruiting Early Phase 1 University of Pennsylvania · Philadelphia, Pennsylvania · NCT04649008

• RAP-219 long-acting injectable safety and PK study in healthy adults

  This early study tests RAP-219-LAI in healthy adults to see how it behaves in the body and whether it is safe and tolerable.

  Recruiting Phase 1 Rapport Therapeutics Inc. · Adelaide · NCT07923097

• Why People with Epilepsy Get More Infections

  This study tests whether anti-seizure medicines affect immune function and infection risk in people with epilepsy.

  Recruiting University of Aberdeen · Aberdeen · NCT07903168

• Long-Term Epilepsy Outcomes in Children After Perinatal Stroke

  This study looks at how epilepsy progresses in kids who had a stroke before 28 days old to see how their seizures and syndromes evolve over time.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT07898397

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.