Clinical trial Recruiting at 1 site Early Phase 1 Interventional Ages 18 and up

Suprachoroidal triamcinolone for macular edema from non-infectious uveitis after failed sub-Tenon injections

Official title: Suprachoroidal Triamcinolone in Macular Edema for Patients With Non-Infectious Uveitis Resistant to Subtenon Triamcinolon

Run by University of Baghdad · NCT07145008 · Data updated 2026-11-12

We will test whether a single suprachoroidal triamcinolone injection can improve vision and reduce central retinal swelling in people with macular edema from non-infectious uveitis who did not improve after sub-Tenon steroid injections.

Quick facts

PhaseEarly Phase 1
Study typeInterventional
Ages18 Years and up
SexAll
Enrollment20 (estimated)
SponsorUniversity of Baghdad
Academic / other
Locations1 site (Baghdad)
StatusRecruiting
StartedSeptember 1, 2024
Main results expectedJune 1, 2025
Study endsDecember 1, 2026
Registry record updatedAugust 28, 2025
Trial IDNCT07145008 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) with non-infectious uveitis causing macular edema of less than four months' duration that persisted despite posterior sub-Tenon triamcinolone are ideal candidates.

Probably not a fit

Patients with epiretinal membrane–associated macular edema, infectious uveitis, children under 18, or chronic macular edema beyond the specified duration are unlikely to benefit or are excluded.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants receive a baseline eye exam including vision testing, slit-lamp exam, and OCT retinal imaging. They then receive one suprachoroidal triamcinolone injection under topical anesthetic in a sterile operating-room setting with standard monitoring. Follow-up visits occur about 1 month and 3 months after treatment with repeat vision tests and OCT scans to measure change in visual acuity and retinal thickness. Participants are instructed to contact the clinic for new pain, redness, floaters, or worsening vision.

Why it matters

Potential benefit: If successful, the procedure could improve vision and reduce central retinal swelling in patients whose uveitic macular edema did not respond to sub-Tenon steroid injections.

How similar studies have gone: Suprachoroidal delivery of triamcinolone and similar approaches have shown promising results in prior clinical work for uveitic macular edema, so this builds on emerging evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Non-infectious uveitis complicated with macular edema
* Uveitic macular edema of less than four months' duration
* Macular edema persisted despite lack of intra-ocular inflammation
* No response to posterior sub-Tenon triamcinolone acetonide injections

Exclusion Criteria:

* Those with epiretinal membrane-associated macular edema
* Below 18 years

Where it's running

  • Ibn Al-Haitham Eye Teaching Hospital
    Baghdad, Iraq
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.