Supporting caregivers of children with rare neurogenetic conditions through telehealth

Optimizing a Personalized Health Approach for Virtually Treating High-risk Caregivers During COVID-19 and Beyond

Not applicable Interventional Purdue University · NCT05999448

This study is testing different online support programs to see which ones help caregivers of children with rare neurogenetic conditions the most.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment800 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorPurdue University Academic / other
Locations1 site (West Lafayette, Indiana)
Trial IDNCT05999448 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to identify the most effective telehealth-based support programs for caregivers of children with rare neurogenetic conditions. It will utilize a personalized health algorithm to match caregivers to appropriate digital health treatments based on their individual needs and circumstances. Participants will engage in a 12-week program that may include self-guided resources, individual and group therapies, and peer-to-peer coaching. Throughout the program, caregivers will complete questionnaires to assess their experiences and the effectiveness of the support provided.

Who should consider this trial

Good fit: Ideal candidates are caregivers or legal guardians of children aged 2-35 with a neurogenetic condition that causes moderate to severe intellectual disability.

Not a fit: Patients who may not benefit include those with serious mental illnesses or active addictions that cannot be adequately addressed through the study's treatments.

Why it matters

Potential benefit: If successful, this study could significantly improve the mental health and well-being of caregivers, enhancing their ability to support their children.

How similar studies have performed: Previous studies have shown initial feasibility and acceptability of telehealth interventions for caregivers, suggesting potential for success in this novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Caregiver and legal guardian of child age 2-35 with neurogenetic condition
* Child's syndrome must (1) have an established genetic cause, (2) affect the brain, resulting in moderate to severe intellectual disability in the majority of patients
* Reside in US
* Fluent in English (spoken and written)
* Seeking support for caregiver mental health/well-being and/or caregiving needs

Exclusion Criteria:

* Serious mental illness or active addiction that would be inadequately addressed through dosage of treatments
* Actively in treatment that would be redundant with those offered in the protocol
* Child's syndrome is not commonly associated with (1) life expectancy less than 35 years or (2) deterioration of previously gained skills.

Additional treatment-specific inclusion criteria are embedded in the experimental algorithm that will be adjusted through Aim 1.

Where this trial is running

West Lafayette, Indiana

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions CaregiversParents
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.