Sunrise device vs PSG to guide CPAP decisions in adults with obstructive sleep apnea
Official title: Treatment Failure of Continuous Positive Airway Pressure (CPAP) in Patients With Obstructive Sleep Apnea Syndrome (OSA): A Randomized Controlled Trial Comparing Polysomnography and the Sunrise Device to Drive Treatment-Adjustment Decisions.
Run by University Hospital, Grenoble · NCT07530302 · Data updated 2026-11-12
We are testing whether using the Sunrise home-monitoring device can guide CPAP treatment decisions as well as the standard overnight lab PSG in adults with obstructive sleep apnea whose CPAP still isn’t fully controlling their condition.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 85 Years |
| Sex | All |
| Enrollment | 105 (estimated) |
| Sponsor | University Hospital, Grenoble Academic / other |
| Locations | 1 site (Grenoble) |
| Status | Recruiting |
| Started | June 10, 2026 |
| Main results expected | September 2029 |
| Study ends | September 2029 |
| Registry record updated | June 17, 2026 |
| Trial ID | NCT07530302 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 to 85 with obstructive sleep apnea on Resmed CPAP who have residual AHI greater than 10 per hour and have smartphone/internet access.
✕Probably not a fit
Patients whose sleep-disordered breathing is not adequately captured by Sunrise metrics or whose CPAP needs cannot be appropriately managed without PSG may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized cross-over study compares one-night Sunrise-based assessments to one-night in-lab polysomnography (PSG) for guiding CPAP therapy adjustments in adults with obstructive sleep apnea who have residual events on CPAP. Participants undergo both Sunrise and PSG assessments, with and without CPAP, and CPAP therapy is reviewed based on each method’s results. Sunrise records mandibular movements and uses AI to derive sleep and breathing metrics, which are then evaluated against PSG-derived metrics to determine if treatment decisions align. The trial addresses whether Sunrise can provide similar residual AHI and other sleep parameter information as PSG, potentially offering a cost-effective, accessible alternative for monitoring CPAP efficacy.
Why it matters
Potential benefit: If successful, Sunrise-guided decisions could streamline follow-up visits, reduce the need for overnight PSG, and improve access to CPAP optimization.
How similar studies have gone: Previous validation studies show strong agreement between Sunrise-derived metrics and PSG, but this is among the first randomized cross-over trials using Sunrise to guide CPAP treatment decisions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 to 85 years * Patients treated with Resmed CPAP * Residual apnea-hypopnea index under CPAP (rAHI(CPAP) \> 10 events/hour) * Access to a smartphone and home internet connection, and ability to use a mobile application * Signed informed consent * Affiliated with, or beneficiary of, a national health insurance program Exclusion Criteria: * Severe chronic obstructive or restrictive pulmonary disease, with or without supplemental oxygen * Unstable cardiovascular disease or severe heart failure requiring hospitalization within the past 3 months, or meeting New York Heart Association (NYHA) class III or IV criteria * Conditions affecting mandibular condyle rotation or temporomandibular joint function * Refusal to shave excessive facial hair when required for proper placement of the Sunrise device * Participation in another interventional clinical study or currently within an exclusion period of another study * Individuals who, in the investigator's judgment, are unlikely to comply with study procedures or requirements * Individuals who cannot be contacted in case of emergency * Persons protected under French Public Health Code articles L1121-5, L1121-6, and L1121-8 (including pregnant or breastfeeding women, persons deprived of liberty, individuals under psychiatric care under articles L.3212-1 or L.3213-1, individuals admitted to healthcare or social institutions for reasons other than research, and persons under legal protection or unable to provide informed consent) * Staff members with a hierarchical relationship to the principal investigator
Where it's running
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CHU Grenoble Alpes
Grenoble, France Recruiting
Study contacts
- Study coordinator: Marie JOYEUX-FAURE, Pr
- Email: MJoyeuxfaure@chu-grenoble.fr
- Phone: +33(0)476767166
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Boosting the blood pressure benefit of CPAP for people with obstructive sleep apnea
This project will test whether CPAP lowers blood pressure more in some adults with obstructive sleep apnea and whether adding a short sleep medication for people who wake up at night improves that blood pressure effect.
-
CPAP for sleep apnea–triggered atrial fibrillation
This pilot tests whether alternating periods with and without CPAP can cut down AF episodes and improve AF-related quality of life for people with paroxysmal AF and moderate to severe obstructive sleep apnea.
-
Using wearable technology to improve sleep staging
This study is testing whether using wearable devices and smartphones can help improve how we track and understand sleep patterns in healthy young adults compared to traditional sleep studies.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.