Study on how iodine nutrition affects thyroid function in pregnant women
Longitudinal Study on the Influence of Iodine Nutrition Status on Thyroid Function of Childbearing Age Women During Pregnancy and 6 Weeks Postpartum
Beijing Friendship Hospital · NCT05677581
This study is testing how iodine nutrition affects thyroid function in pregnant women to help create better guidelines for their iodine intake.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2100 (estimated) |
| Sex | Female |
| Sponsor | Beijing Friendship Hospital (other) |
| Locations | 1 site (Beijing) |
| Trial ID | NCT05677581 on ClinicalTrials.gov |
What this trial studies
This observational study aims to analyze the changes in iodine nutrition status and thyroid function among women of childbearing age during pregnancy and six weeks postpartum. It will track urinary iodine levels and thyroid function at different stages of pregnancy and assess dietary iodine intake through questionnaires. The goal is to develop tailored iodine intake programs for pregnant women and improve monitoring systems for maternal iodine nutrition. Participants will include healthy women aged 20-40 who meet specific health criteria.
Who should consider this trial
Good fit: Ideal candidates are healthy women aged 20-40 who are primigravida and meet specific health criteria.
Not a fit: Patients with a history of thyroid disease or those who are multiple pregnancies or multigravida may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved iodine intake recommendations for pregnant women, enhancing maternal and fetal health.
How similar studies have performed: While iodine nutrition's impact on thyroid function has been studied, this specific longitudinal approach in the context of pregnancy is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
8-12 weeks healthy maternal: Inclusion Criteria: * primigravida * no chronic hypertension, thromboembolic disease, severe gastrointestinal, cardiopulmonary and liver diseases before pregnancy * no systemic lupus erythematosus, rheumatic diseases and other connective tissue diseases or immune diseases before pregnancy * no adrenocortical hyperplasia, pituitary endocrine diseases and other diseases before pregnancy Exclusion Criteria: * multiple pregnancies and multigravida * a history of type I or type II diabetes before pregnancy * a clear history of thyroid diseases before pregnancy * taking drugs that affect thyroid function and/or blood sugar before or during early pregnancy Healthy women of childbearing age: Inclusion Criteria: * 20-40 years old * no chronic hypertension, thromboembolic disease, severe gastrointestinal, cardiopulmonary and liver diseases * no systemic lupus erythematosus, rheumatic diseases and other connective tissue diseases or immune diseases * no adrenocortical hyperplasia, pituitary endocrine diseases and other diseases Exclusion Criteria: * a history of type I or type II diabetes * a clear history of thyroid diseases * taking drugs that affect thyroid function and/or blood sugar
Where this trial is running
Beijing
- Beijing Friendship Hospital ,Capital Medical University — Beijing, China (RECRUITING)
Study contacts
- Study coordinator: Yan Long, Chief Physician/Professor
- Email: longyan_doc@163.com
- Phone: 13671148911
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Thyroid Function, Iodine Nutrition Status