Study on how carotenoids in diet affect young children's health

Observational Validation of Skin Carotenoid Biomarker of Infant and Toddler Carotenoid Intake

Observational Baylor College of Medicine · NCT05869760

This study looks at how eating colorful fruits and vegetables affects the health and vision of young children by checking the levels of carotenoids in their blood and skin.

Quick facts

Study typeObservational
Enrollment208 (estimated)
Ages3 Months to 24 Months
SexAll
SponsorBaylor College of Medicine Academic / other
Locations1 site (Houston, Texas)
Trial IDNCT05869760 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore the relationship between carotenoid intake from foods and the visual development of infants and toddlers. Researchers will measure carotenoid levels in the blood and skin to assess dietary intake and its potential impact on health outcomes. The study focuses on understanding how these phytochemicals, found in colorful fruits and vegetables, contribute to children's nutrition and overall well-being. By utilizing advanced measurement technologies, the study seeks to provide insights into the role of carotenoids in early life nutrition.

Who should consider this trial

Good fit: Ideal candidates for this study are healthy infants and toddlers aged 3 months to 2 years who meet specific growth criteria and have guardians that can communicate in English.

Not a fit: Patients with diagnosed metabolic, absorptive, or endocrine conditions, or those with food allergies or intolerances, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of how carotenoid intake supports visual development and overall health in young children.

How similar studies have performed: While studies on carotenoids in adults have shown promising results, this specific approach in young children is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* healthy
* born at term (more than or equal to 37 weeks gestation)
* between the 1st to 99th weight for age percentile at 3 months of age
* participating guardian speaks, reads, and understands English
* guardian categorizes child as non-Hispanic white, Hispanic white, Asian, or non-Hispanic Black

Exclusion Criteria:

* physician-diagnosed metabolic, absorptive, or endocrine condition
* diagnosed food intolerance or allergy
* has a sibling enrolled in the study

Where this trial is running

Houston, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Healthy NutritionHealthy Dietinfanttoddlercarotenoidsbiomarkersfood intakevisual development
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.