Study of family connections in blood and lymph cancers

Genetic Epidemiology of Lymphoproliferative Disorders

Observational Mayo Clinic · NCT00626496

This study looks at families with multiple members diagnosed with blood and lymph cancers to see if genetics and environmental factors play a role in their development.

Quick facts

Study typeObservational
Enrollment3000 (estimated)
Ages18 Years to 100 Years
SexAll
SponsorMayo Clinic Academic / other
Locations1 site (Rochester, Minnesota)
Trial IDNCT00626496 on ClinicalTrials.gov

What this trial studies

This observational study investigates the genetic and environmental factors that may contribute to the development of blood and lymph cancers, such as lymphoma and leukemia, which often show familial clustering. By examining families with multiple affected members, researchers aim to identify patterns and potential risk factors associated with these disorders. Participants will include families with at least two living blood relatives diagnosed with a lymphoproliferative disorder. The study will collect data on family history and environmental exposures to better understand the etiology of these cancers.

Who should consider this trial

Good fit: Ideal candidates for this study are families with at least two living blood relatives diagnosed with a lymphoproliferative disorder.

Not a fit: Patients without a family history of lymphoproliferative disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding of the risk factors for blood and lymph cancers, potentially guiding prevention and early detection strategies.

How similar studies have performed: Other studies have shown success in understanding familial patterns in cancer, suggesting that this approach could yield valuable insights.

Eligibility criteria

Show full inclusion / exclusion criteria
At least 2 living, blood related relatives, affected with a lymphoproliferative disorder.

Where this trial is running

Rochester, Minnesota

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lymphoma, Non-HodgkinLeukemia, Lymphocytic, Chronic, B-CellLymphoma, B-CellMonoclonal B-Cell LymphocytosisMultiple Myeloma
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.