Clinical trial Recruiting at 1 site Observational Ages 18 to 100

Study of family connections in blood and lymph cancers

Official title: Genetic Epidemiology of Lymphoproliferative Disorders

Run by Mayo Clinic · NCT00626496 · Data updated 2026-11-12

This study looks at families with multiple members diagnosed with blood and lymph cancers to see if genetics and environmental factors play a role in their development.

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Quick facts

Study typeObservational
Ages18 Years to 100 Years
SexAll
Enrollment3000 (estimated)
SponsorMayo Clinic
Academic / other
Locations1 site (Rochester, Minnesota)
StatusRecruiting
StartedApril 1, 2004
Main results expectedDecember 31, 2029
Study endsDecember 31, 2029
Registry record updatedNovember 2, 2026
Trial IDNCT00626496 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are families with at least two living blood relatives diagnosed with a lymphoproliferative disorder.

Probably not a fit

Patients without a family history of lymphoproliferative disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the genetic and environmental factors that may contribute to the development of blood and lymph cancers, such as lymphoma and leukemia, which often show familial clustering. By examining families with multiple affected members, researchers aim to identify patterns and potential risk factors associated with these disorders. Participants will include families with at least two living blood relatives diagnosed with a lymphoproliferative disorder. The study will collect data on family history and environmental exposures to better understand the etiology of these cancers.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding of the risk factors for blood and lymph cancers, potentially guiding prevention and early detection strategies.

How similar studies have gone: Other studies have shown success in understanding familial patterns in cancer, suggesting that this approach could yield valuable insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
At least 2 living, blood related relatives, affected with a lymphoproliferative disorder.

Where it's running

  • Mayo Clinic
    Rochester, Minnesota, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.