Strengthening the thumb muscle for arthritis relief

Strengthening of the First Dorsal Interosseous for Thumb Carpometacarpal Osteoarthritis

Not applicable Interventional Massachusetts General Hospital · NCT03177577

This study tests whether specific exercises and splinting can help people with thumb arthritis feel less pain and improve their hand function.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years and up
SexAll
SponsorMassachusetts General Hospital Academic / other
Locations1 site (Boston, Massachusetts)
Trial IDNCT03177577 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of strengthening the first dorsal interosseous muscle in patients suffering from thumb carpometacarpal osteoarthritis. It aims to determine whether targeted exercises can improve pain and function in individuals experiencing this common age-related condition. Participants will undergo a treatment regimen that includes splinting and specific strengthening exercises over a 12-week period. The study builds on previous findings that suggest enhancing muscle strength can stabilize the thumb joint and reduce symptoms.

Who should consider this trial

Good fit: Ideal candidates are English-speaking adults aged 18 and older who are currently receiving splint treatment for thumb carpometacarpal osteoarthritis.

Not a fit: Patients with rheumatoid arthritis or post-traumatic carpometacarpal osteoarthritis, as well as those who have recently received corticosteroid injections, may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide a low-cost, effective non-surgical option for improving thumb function and reducing pain in patients with osteoarthritis.

How similar studies have performed: Previous studies have shown promising results with similar approaches focusing on muscle strengthening for thumb osteoarthritis, indicating potential efficacy.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* At least 18 years old
* English-speaking
* Splint treatment for thumb carpometacarpal (CMC) osteoarthritis

Exclusion Criteria:

* Less than 18 years old
* Rheumatoid Arthritis or post-traumatic carpometacarpal (CMC) osteoarthritis
* Patients that received a corticosteroid injection during the appointment for treatment of thumb carpometacarpal (CMC) osteoarthritis

Where this trial is running

Boston, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Thumb OsteoarthritisFirst Dorsal Interosseous Strengthening
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.