Strength training with blood flow restriction after hip replacement
Clinical Randomized Trial of the Influence of Rehabilitation Therapy Using Strength and Blood Flow Restriction Training on Muscular Fitness and Regeneration After Elective Hip Replacement
NA · University Hospital, Bonn · NCT07043127
This trial tests whether adding supervised strength training with blood flow restriction to standard outpatient rehabilitation helps people who had a recent total hip replacement regain muscle strength and support muscle regeneration.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Bonn (other) |
| Locations | 1 site (Bonn, North Rhine-Westphalia) |
| Trial ID | NCT07043127 on ClinicalTrials.gov |
What this trial studies
Participants who had total hip arthroplasty within the past four weeks will join outpatient exercise therapy at the University Hospital Bonn. They will receive either true blood flow restriction (BFR) combined with strength training or a sham-BFR protocol alongside routine exercise therapy units (ETM01) following local RTS hip/knee therapy standards. The interventions are delivered within the outpatient rehabilitation framework to determine effects on muscular fitness and markers of muscle regeneration. Outcomes will compare functional muscle performance and recovery between the BFR and sham groups over the rehabilitation period.
Who should consider this trial
Good fit: Adults who are able to participate in outpatient rehabilitation and who had total hip arthroplasty within the past four weeks are the intended participants.
Not a fit: Patients with sickle cell anemia, iatrogenic vascular changes in the lower limb (for example stents), open wounds or infections of the lower extremity, or those not cleared for outpatient rehab are unlikely to benefit or be eligible.
Why it matters
Potential benefit: If successful, this approach could speed recovery of muscle strength and improve muscle regeneration after hip replacement.
How similar studies have performed: Blood flow restriction combined with low-load strength training has shown positive effects on muscle strength and hypertrophy in other orthopedic and postoperative settings, though data specifically after total hip arthroplasty are more limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ability for Rehabilitation * Total Hip Arthroplasty Surgery during the last 4 Weeks Exclusion Criteria: * Sickle Cell Anemia * Iatrogenic changes in the vessels of the lower Extremity (e.g. Stents) * Open Wounds or Infections of the lower Extremity
Where this trial is running
Bonn, North Rhine-Westphalia
- University Hospital Bonn — Bonn, North Rhine-Westphalia, Germany (RECRUITING)
Study contacts
- Study coordinator: Alexander Franz, Dr. med., B.Sc.
- Email: alexander.franz@ukbonn.de
- Phone: +491703750718
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Total Hip Arthroplasty