Strength and endurance training for people with Parkinson's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effects of combining strength training with aerobic training on patients with idiopathic Parkinson's disease. Participants will engage in a 12-week intervention consisting of twice-weekly training sessions, with assessments conducted before, after, and three months post-intervention. The study will measure physical performance, disease severity, blood biomarkers, and quality of life to determine if the combined training offers greater benefits than aerobic training alone.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age ≥18 years
* diagnosis of idiopathic Parkinson´s disease
* Hoehn-Yahr Scale ≤ 2,5
* stable dopaminergic medication

Exclusion Criteria:

* age ≥75 years
* Hoehn-Yahr Scale ≥ 2,5
* deep brain stimulation
* presence of freezing
* Camptocormia
* inability to walk without support
* inability to perform study procedures
* limiting co-morbidities
* attendance at training sessions below 70%

Where it's running

• Department of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague
  Prague, Prague, Czechia Recruiting

Study contacts

• Study coordinator: Jakub Vítek, MSc.
• Email: jakub.vitek@vfn.cz
• Phone: +420 224 965 513

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.