Strength and endurance training for people with Parkinson's disease
Strength-Endurance Circuit Training in Parkinson's Disease: Effects on Disease Severity, Physical Performance, Blood Biomarkers and Quality of Life.
NA · General University Hospital, Prague · NCT06893055
This study is testing if combining strength training with aerobic exercise can help people with Parkinson's disease improve their physical performance and quality of life better than just aerobic exercise alone.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | General University Hospital, Prague (other) |
| Locations | 1 site (Prague, Prague) |
| Trial ID | NCT06893055 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effects of combining strength training with aerobic training on patients with idiopathic Parkinson's disease. Participants will engage in a 12-week intervention consisting of twice-weekly training sessions, with assessments conducted before, after, and three months post-intervention. The study will measure physical performance, disease severity, blood biomarkers, and quality of life to determine if the combined training offers greater benefits than aerobic training alone.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 75 with a diagnosis of idiopathic Parkinson's disease and a Hoehn-Yahr Scale score of 2.5 or lower.
Not a fit: Patients over 75 years old, those with advanced disease severity, or those unable to participate in the training sessions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance physical performance and quality of life for patients with Parkinson's disease.
How similar studies have performed: Previous studies have shown positive outcomes with combined strength and endurance training in similar patient populations, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age ≥18 years * diagnosis of idiopathic Parkinson´s disease * Hoehn-Yahr Scale ≤ 2,5 * stable dopaminergic medication Exclusion Criteria: * age ≥75 years * Hoehn-Yahr Scale ≥ 2,5 * deep brain stimulation * presence of freezing * Camptocormia * inability to walk without support * inability to perform study procedures * limiting co-morbidities * attendance at training sessions below 70%
Where this trial is running
Prague, Prague
- Department of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague — Prague, Prague, Czechia (RECRUITING)
Study contacts
- Study coordinator: Jakub Vítek, MSc.
- Email: jakub.vitek@vfn.cz
- Phone: +420 224 965 513
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Parkinson Disease, Idiopathic, Parkinson Disease, Strength training, Endurance training, Physiotherapy, Irisin, Quality of Life, Physical performance