Strasbourg cohort of people with adrenal cortical carcinoma
Official title: Characterization of the Strasbourg Cohort of Patients With Adrenal Cortex Carcinoma
Run by University Hospital, Strasbourg, France · NCT07335679 · Data updated 2026-11-12
This project collects clinical, imaging and pathology information from adults treated at Strasbourg University Hospital to better understand adrenal cortical carcinoma.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | University Hospital, Strasbourg, France Academic / other |
| Locations | 1 site (Strasbourg) |
| Status | Recruiting |
| Started | June 10, 2025 |
| Main results expected | June 2027 |
| Study ends | June 10, 2027 |
| Registry record updated | January 13, 2026 |
| Trial ID | NCT07335679 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18 years) with histopathologically confirmed adrenal cortical carcinoma who are or were followed at Strasbourg University Hospital between January 1, 2000 and May 31, 2025 are eligible.
✕Probably not a fit
Patients whose tumors were reclassified as non-ACC, individuals not followed at Strasbourg University Hospital, and pediatric patients are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational cohort compiles retrospective and prospective clinical, imaging, biochemical and histopathologic data from adults diagnosed with adrenal cortical carcinoma and followed at Strasbourg University Hospital between January 1, 2000 and May 31, 2025. Inclusion requires histopathologic confirmation of the adrenal cortical tumor and excludes tumors later reclassified as non-ACC. Collected data will include Weiss score, Ki-67, hormonal secretion status, imaging features, treatments and outcomes. The work is purely descriptive and aims to define disease patterns and prognostic markers to inform future research and clinical decisions.
Why it matters
Potential benefit: If successful, this cohort could improve understanding of tumor biology and outcomes to help doctors diagnose, prognose and design future trials for ACC.
How similar studies have gone: Previous single-center and registry cohorts have yielded useful descriptive data on ACC but are limited by rarity of the disease, so this project builds on existing observational work rather than introducing a novel intervention.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult subject (≥ 18 years old) * Subjects followed at Strasbourg University Hospital for adrenal cortical carcinoma diagnosed between January 1, 2000, and May 31, 2025 Exclusion Criteria: \- Tumor reclassified as non-SCC by histopathology
Where it's running
-
Service d'Endocrinologie, Diabétologie, Nutrition - CHU de Strasbourg - France
Strasbourg, France Recruiting
Study contacts
- Study coordinator: Philippe BALTZINGER, MD
- Email: philippe.baltzinger@chru-strasbourg.fr
- Phone: 33 3 88 12 75 82
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Cemiplimab maintenance for advanced adrenocortical carcinoma
This trial will test whether giving cemiplimab as maintenance immunotherapy after first-line EDP-M chemotherapy can delay progression in adults with advanced adrenocortical carcinoma who achieved a response or stable disease.
-
Combining PD-1 inhibitor with Apatinib and Mitotane for advanced adrenal cancer treatment
This study is testing a new combination of three medications to see if it can help people with advanced adrenal cancer who haven't had treatment yet.
-
Personalized mRNA vaccine for advanced endocrine tumors
This study is testing a personalized mRNA vaccine to see if it can help patients with advanced endocrine tumors who haven't had success with standard treatments.
-
Cabozantinib plus pembrolizumab for advanced or unresectable adrenal cortical cancer
This trial tests whether adding cabozantinib to pembrolizumab can shrink or control advanced, metastatic, or unresectable adrenal cortical cancer.
-
Combining PDS01ADC with targeted liver chemotherapy for certain cancers
This study is testing if a new cancer treatment that combines an immune booster with targeted liver chemotherapy can help people with certain advanced cancers feel better and live longer.
-
Preoperative targeted radiation before surgery for recurrent abdominal adrenocortical carcinoma
This study tests giving a short course of focused external beam radiation before surgery in adults whose adrenocortical cancer has come back and appears removable.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.