Stop for Stress: online versus group program for work-related stress

Stop for Stress - En Sammenligning af Online og Gruppebaseret Behandling for Arbejdsrelateret Stress

Not applicable Interventional Aarhus University Hospital · NCT06799403

This project tests whether a therapist-guided online version of Stop for Stress works as well as the in-person group program for adults with significant work-related stress.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment220 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorAarhus University Hospital Academic / other
Locations2 sites (Aarhus, Central Region Denmark and 1 other locations)
Trial IDNCT06799403 on ClinicalTrials.gov

What this trial studies

This is a two-armed, multicenter randomized trial enrolling 220 employed adults with severe work-related stress who score at least 20 on the PSS-10 and have symptom duration over four weeks. Participants are randomized 1:1 to a therapist-assisted online delivery of the Stop for Stress program or to an evidence-based face-to-face group format, with recruitment at two occupational medicine departments in Central Denmark. The trial excludes cases where interpersonal violence, primarily non-work stressors, severe psychiatric disorders, or substance abuse are the main problems. The study also aims to identify markers that predict better outcomes in each delivery format and to compare return-to-work outcomes between arms.

Who should consider this trial

Good fit: Employed adults experiencing significant work-related stress (PSS-10 ≥20) who can commit to the program and either attend group sessions at a study center or use a home computer/tablet with internet access are ideal candidates.

Not a fit: People whose primary problems are workplace bullying, severe psychiatric disorders, ongoing substance abuse, or major non-work stressors are unlikely to benefit from this intervention.

Why it matters

Potential benefit: If successful, the trial could expand access to an effective, scalable online program that reduces work-related stress and supports return to work.

How similar studies have performed: Prior research and pilot data indicate that online stress-management programs can achieve effects similar to face-to-face group interventions, and the Stop for Stress online format showed promising pilot results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Current employment and significant work-related stressors
* Perceived Stress Scale (PSS-10) score ≥20 and symptom duration \>4 weeks
* In case of full-time sick leave, return to work must be planned concurrent with the intervention
* Access to a computer or tablet with internet connection at home

Exclusion Criteria:

* Interpersonal difficulties, bullying, harassment, violence, threats, and traumatic events as primary stressor
* Severe stressors outside of work
* Symptoms meeting diagnostic criteria for anxiety, depression or severe psychiatric illnesses requiring specialized treatment
* Current abuse of alcohol and/or psychoactive drugs

Where this trial is running

Aarhus, Central Region Denmark and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Work-Related Stresswork-related stressonline interventiongroup interventionreturn-to-work
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.