Staples versus stitches for closing episiotomy wounds in first-time mothers

THE EFFECT OF STAPLER VERSUS SKIN SUTURING ON PAIN AND WOUND HEALING AFTER EPISIOTOMY REPAIR IN PRIMIPAROUS WOMEN: A RANDOMIZED CONTROLLED TRIAL

Not applicable Interventional Ege University · NCT07383623

This test will see if using surgical staples instead of stitches to close an episiotomy reduces postpartum pain and improves wound healing for first-time mothers.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment24 (estimated)
Ages18 Years to 49 Years
SexFemale
SponsorEge University Academic / other
Locations1 site (Izmir, İzmir)
Trial IDNCT07383623 on ClinicalTrials.gov

What this trial studies

This randomized controlled trial will enroll primiparous women who require an episiotomy during vaginal delivery and randomly assign them to skin closure with surgical staples or with absorbable sutures. Postpartum pain will be measured with standardized pain scales and analgesic use, and wound healing will be assessed during scheduled postpartum visits. Women with major (3rd/4th degree) tears, conditions that impair wound healing, or complicated deliveries are excluded. The trial compares short-term pain and wound recovery between the two closure techniques to guide clinical decisions about episiotomy repair.

Who should consider this trial

Good fit: Ideal candidates are primiparous women aged 18 or older with a term, low-risk singleton pregnancy who require a first- or second-degree episiotomy and can deliver and follow up at the study hospital.

Not a fit: Women with third- or fourth-degree tears, obesity, active vaginal infection, conditions that impair wound healing (for example diabetes or immunosuppression), neonatal complications, or complicated deliveries are unlikely to benefit from the interventions tested here.

Why it matters

Potential benefit: If successful, using staples could reduce postpartum pain and speed wound recovery, improving comfort and early maternal-infant interactions.

How similar studies have performed: Previous small trials and surgical literature comparing staples and sutures for skin or perineal closure have shown mixed results, so the approach is not yet conclusively proven for episiotomy repair.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Term pregnancy (≥ 37 weeks)
* Low-risk pregnancy (no obstetric risk factors)
* Not receiving oxytocin induction during latent or active labor
* Singleton pregnancy with a live fetus
* No psychiatric disorder
* No substance abuse
* Primiparous women (first vaginal birth)
* Presence of 1st or 2nd degree perineal tear
* Able to read, understand, and voluntarily provide written and verbal informed consent.

Exclusion Criteria:

* Apgar score \< 7 at 1 minute and/or 5 minutes
* Neonatal anomaly
* Use of \>10 mL analgesic during episiotomy repair beyond routine practice
* Obesity
* Vaginal infection or vaginal lesion
* Maternal conditions impairing wound healing (e.g., diabetes mellitus, immunosuppression, coagulation disorders)
* 3rd or 4th degree perineal tear
* Shoulder dystocia / difficult delivery

Where this trial is running

Izmir, İzmir

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Episiotomyepisiotomystaplerprimiparous women
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.