Standardized subcutaneous LMWH injections for people with cardiovascular disease.
Official title: The Effect of Standardizing Procedures for Subcutaneous Injections of Low-molecular-weight Heparin on Patients With Cardiovascular Diseases: A Cluster Randomized Controlled Trial
Run by The Hong Kong Polytechnic University · NCT06776159 · Data updated 2026-11-12
This will test whether using a standardized method for giving twice-daily subcutaneous LMWH injections reduces bruising and pain for people with cardiovascular disease in cardiac care units.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 180 (estimated) |
| Sponsor | The Hong Kong Polytechnic University Academic / other |
| Locations | 1 site (Hong Kong) |
| Status | Recruiting |
| Started | June 24, 2025 |
| Main results expected | April 30, 2027 |
| Study ends | April 30, 2027 |
| Registry record updated | September 18, 2026 |
| Trial ID | NCT06776159 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Chinese adults in cardiac care units in Hong Kong with cardiovascular disease who are prescribed twice-daily subcutaneous LMWH and can consent are the ideal candidates.
✕Probably not a fit
Patients who are unconscious, cognitively impaired, refuse to participate, or who are not receiving twice-daily subcutaneous LMWH are unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares a standardized protocol for subcutaneous low-molecular-weight heparin (LMWH) injections with the current active control procedure in cardiac care units. Nurses will apply the standardized injection technique to patients prescribed twice-daily LMWH and outcomes such as injection-site bruising and pain will be recorded. The protocol aims to reduce administration-related complications by improving consistency of technique across clinicians. Participants are Chinese adults in Hong Kong cardiac units who can provide consent.
Why it matters
Potential benefit: If successful, the protocol could reduce injection-site bruising and pain and improve patient comfort and safety during LMWH treatment.
How similar studies have gone: Protocol-based approaches to subcutaneous injections have reduced injection-site complications in other settings, but specifically standardized LMWH protocols in cardiac units have been limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients who are in cardiac care units suffering from cardiovascular diseases prescribed with LMWH injections two times per day * Chinese Exclusion Criteria: * cognitively impaired * unconscious * refuse to participate
Where it's running
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Hospital Authority, Hong Kong
Hong Kong, Hong Kong Recruiting
Study contacts
- Principal investigator: Arkers Wong — The Hong Kong Polytechnic University
- Study coordinator: Frankie CHEUNG
- Email: frankie.py.cheung@polyu.edu.hk
- Phone: 852 2766 7991
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.