Staging methods and prognosis for lung cancers with air-filled cysts

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study collects imaging, surgical, and pathological data from patients with histologically confirmed non-small cell lung cancer who have an air-filled cystic component and underwent surgical resection. Investigators will compare alternative tumor-size measurement methods on preoperative chest CT and correlate those imaging measurements with postoperative pathology and patient outcomes. The study will analyze how specific CT features of the cystic lesions relate to pathological characteristics and to survival or recurrence. All data are collected at The Second Xiangya Hospital of Central South University and require complete, high-quality preoperative chest CT scans.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Histologically confirmed non-small cell lung cancer (NSCLC), as verified by biopsy or postoperative pathological examination;
2. Patients who have undergone surgical lung resection;
3. Patients with complete preoperative chest CT imaging data;
4. Preoperative chest CT showing a well-defined gas-containing (air-filled) cystic component within the tumor.

Exclusion Criteria:

1. History of pulmonary diseases that could produce cystic lung lesions (e.g., tuberculosis, pulmonary fungal infections, bullae, emphysema, Lymphangioleiomyomatosis \[LAM\], or Birt-Hogg-Dubé \[BHD\] syndrome);
2. Systemic anti-tumor therapies, including chemotherapy, radiotherapy, or targeted therapies (such as monoclonal antibodies, small-molecule tyrosine kinase inhibitors, among others), were administered prior to enrollment;
3. Patients with concurrent other malignancies;
4. Patients with missing or poor-quality preoperative chest CT imaging data.

Where it's running

• The Second Xiangya Hospital of Central South University
  Changsha, Hunan, China Recruiting

Study contacts

• Study coordinator: Chen Chen
• Email: chenchen1981412@csu.edu.cn
• Phone: +8673185295188

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.