SPIRIT Club exercise platform for adults with chronic brain injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Investigators are partnering with SPIRIT Club to create and refine a dedicated online exercise pathway tailored for adults with chronic brain injury (CBI). They will enroll 60 participants who are at least 9 months post-injury, currently exercise less than 60 minutes per week, can follow simple commands, and meet basic mobility or seated balance requirements. Participants will be randomized so half use the new SPIRIT Club CBI pathway while the other half are monitored for activity, with usability, engagement, and iterative platform improvements tracked in real-world settings. The project is led by Ohio State University with collaboration from NIH and NICHD and involves experts from industry, clinical rehabilitation, and research.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older with chronic brain injury (CBI)
* At least 9 months post-injury
* Is able to able to be able to demonstrate the ability to meet at least one of the following functional mobility scenarios: 1) able to walk with or without an assistive device or with no more than contact guard assist from a caregiver for steadiness checks and proprioceptive support, 2) able to stand up from a chair with no assistance or no more than contact guard assist from a caregiver for steadiness and proprioceptive support, and/or 3) able to maintain steady seated balance in a chair or wheelchair and able to lift at least one limb with minimal assist (\<25%) from a caregiver against gravity
* Currently exercising less than 60 minutes per week
* Able to follow simple commands
* Participant is his/her own legal authorized representative (LAR) or LAR is able to verify they can follow simple commands and participate in study and support consenting and participation processes
* Provides confirmation of medical clearance from physician to participate in moderate levels of activity without supervision from a licensed healthcare provider

Exclusion Criteria:

* Unsafe independent functional mobility observed during the functional mobility screen and no available caregiver/carepartner to facilitate participation in the study and provide assistance while using the SPIRIT Club platform
* Being advised by any healthcare provider to avoid or restrict participation in moderate to high-intensity physical activity
* Uncontrolled blood pressure, unstable angina, severe joint disease, uncontrolled or untreated dizziness or vertigo, or other medical issue precluding exercises leading to lack of clearance from a physician
* \- e.g.,
* Unable to follow simple commands or persistent post-traumatic amnesia
* Presence of expressive aphasia
* Lack of fluency in English
* Unable to follow simple commands or persistent post-traumatic amnesia
* Regular participation (2 or more days per week) in a structured fitness program or platform (e.g., group exercise classes or personal training)
* Regular participation (average of 1 or more days per week) in physical therapy services specifically for brain injury rehabilitation

Where it's running

• Ohio State University Wexner Medical Center
  Columbus, Ohio, United States Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Online memory intervention for people with traumatic brain injury

  This study tests whether an online memory training program can help people with moderate to severe traumatic brain injury improve their memory and brain health.

  Recruiting Toronto Rehabilitation Institute · Toronto, Ontario · NCT04331392

• Exploration of whole-brain radiotherapy with PD-1 inhibitors for brain injury in SCLC

  This study tests whether adding PD-1 inhibitors to chemotherapy and prophylactic brain irradiation helps some small cell lung cancer patients protect the brain.

  Recruiting Guizhou Medical University · Guiyang, Guizhou · NCT07905937

• Informational Needs of Caregivers of Patients in Neuro Rehab: Validating the QBI-R/V

  This study tests a caregiver questionnaire (QBI-R and QBI-V) to see how well it measures caregivers’ informational needs during neuromotor rehabilitation.

  Recruiting at 13 sites Istituti Clinici Scientifici Maugeri SpA · Sciacca, Agrigento and 12 other locations · NCT07903298

• Can a bedside brain scan (fNIRS) detect activity in healthy people and in people with disorders of consciousness

  This observational study tests whether functional near-infrared spectroscopy (fNIRS) can measure brain activity at the bedside in healthy adults and in patients with disorders of consciousness in the Neuro-ICU.

  Recruiting University of California, Los Angeles · Los Angeles, California · NCT07485361

• The Coma Family Program: a resilience program for caregivers of patients with severe brain injury

  This program tests whether the Coma Family Program can better reduce emotional distress in caregivers of patients with severe acute brain injury compared to a health education control.

  Recruiting at 3 sites Icahn School of Medicine at Mount Sinai · Baltimore, Maryland and 3 other locations · NCT07331324

• Program to restore resilience and reduce PTSD after military sexual trauma or intimate partner violence with brain injury

  This trial tests whether adding a web-based emotion regulation program to exposure therapy helps female Veterans with military sexual trauma or intimate partner violence and a history of brain injury reduce PTSD symptoms.

  Recruiting Icahn School of Medicine at Mount Sinai · Houston, Texas · NCT06988787

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.