Speech learning and production in people with Parkinson's
Relationship Between Speech Perceptual Learning and Speech Production in Parkinson's Disease
This project tests whether differences in how people with Parkinson's learn to hear and copy speech sounds are linked to how clearly they speak.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 45 Years and up |
| Sex | All |
| Sponsor | State University of New York at Buffalo Academic / other |
| Locations | 1 site (Buffalo, New York) |
| Trial ID | NCT07403539 on ClinicalTrials.gov |
What this trial studies
This interventional project links speech perception, perceptual learning, and speech production in people with Parkinson's using acoustic measurements. Participants complete tasks that target intensity and rate learning and discrimination while their speech is recorded and analyzed. The study enrolls native North American English speakers with Parkinson's who take levodopa, excludes people with other major neurological, speech, language, or significant hearing disorders, and is conducted at a single site. Results aim to identify predictors of individual differences in how people respond to speech-focused therapies.
Who should consider this trial
Good fit: Ideal candidates are U.S. residents with a Parkinson's diagnosis who are native North American English speakers, take a levodopa-containing medication, and have no other major neurological, speech, language, or significant hearing disorders.
Not a fit: People with significant hearing loss or hearing devices, other major neurological conditions (like stroke or Alzheimer's), non–North American English speakers, or those not taking levodopa are unlikely to benefit from this specific protocol.
Why it matters
Potential benefit: If successful, the findings could lead to more personalized therapies that help people with Parkinson's both understand speech better and speak more clearly.
How similar studies have performed: While traditional speech therapies for Parkinson's have established benefits, linking perceptual learning of speech to production outcomes is relatively novel and has limited prior evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of Parkinson's disease * Native speaker of North American English * Use a drug that includes levodopa * Resident of the United States Exclusion Criteria: * Any history of language, hearing or speech disorder outside of Parkinson's disease * Other gross neurological impairment such as Alzheimer's disease or stroke * Significant hearing loss and/or use of a hearing aid or cochlear implant
Where this trial is running
Buffalo, New York
- State University of New York at Buffalo — Buffalo, New York, United States (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.