Clinical trial Recruiting at 1 site Interventional Ages 45 and up

Speech learning and production in people with Parkinson's

Official title: Relationship Between Speech Perceptual Learning and Speech Production in Parkinson's Disease

Run by State University of New York at Buffalo · NCT07403539 · Data updated 2026-11-12

This project tests whether differences in how people with Parkinson's learn to hear and copy speech sounds are linked to how clearly they speak.

Quick facts

Study typeInterventional
Ages45 Years and up
SexAll
Enrollment50 (estimated)
SponsorState University of New York at Buffalo
Academic / other
Locations1 site (Buffalo, New York)
StatusRecruiting
StartedJanuary 27, 2026
Main results expectedDecember 31, 2027
Study endsDecember 31, 2027
Registry record updatedSeptember 22, 2026
Trial IDNCT07403539 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are U.S. residents with a Parkinson's diagnosis who are native North American English speakers, take a levodopa-containing medication, and have no other major neurological, speech, language, or significant hearing disorders.

Probably not a fit

People with significant hearing loss or hearing devices, other major neurological conditions (like stroke or Alzheimer's), non–North American English speakers, or those not taking levodopa are unlikely to benefit from this specific protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional project links speech perception, perceptual learning, and speech production in people with Parkinson's using acoustic measurements. Participants complete tasks that target intensity and rate learning and discrimination while their speech is recorded and analyzed. The study enrolls native North American English speakers with Parkinson's who take levodopa, excludes people with other major neurological, speech, language, or significant hearing disorders, and is conducted at a single site. Results aim to identify predictors of individual differences in how people respond to speech-focused therapies.

Why it matters

Potential benefit: If successful, the findings could lead to more personalized therapies that help people with Parkinson's both understand speech better and speak more clearly.

How similar studies have gone: While traditional speech therapies for Parkinson's have established benefits, linking perceptual learning of speech to production outcomes is relatively novel and has limited prior evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosis of Parkinson's disease
* Native speaker of North American English
* Use a drug that includes levodopa
* Resident of the United States

Exclusion Criteria:

* Any history of language, hearing or speech disorder outside of Parkinson's disease
* Other gross neurological impairment such as Alzheimer's disease or stroke
* Significant hearing loss and/or use of a hearing aid or cochlear implant

Where it's running

  • State University of New York at Buffalo
    Buffalo, New York, United States
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.