Soothing moisturizing lotion for adults with atopic eczema in Malaysia
Clinical Evaluation of a Soothing Moisturizing Lotion in Individuals With Atopic Eczema
NA · USMARI Research & Innovation Centre · NCT07463079
This will test whether a soothing moisturizing lotion helps adults in Malaysia with mild to moderate atopic eczema improve their skin and is safe over four weeks.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 15 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | USMARI Research & Innovation Centre (industry) |
| Drugs / interventions | methotrexate |
| Locations | 1 site (Petaling Jaya, Selangor) |
| Trial ID | NCT07463079 on ClinicalTrials.gov |
What this trial studies
This single-center interventional study in Petaling Jaya will provide adults with mild to moderate atopic eczema a soothing moisturizing lotion to use for four weeks, with skin assessments at baseline and week 4. Eligible participants are Malaysian adults aged 18 or older with EASI scores between 10 and 20 and no recent topical or systemic eczema treatments. The study will collect safety data, measure changes in eczema lesion severity using clinical scoring, and record participant satisfaction after product use. The main outcomes are tolerability, change in clinical skin signs, and user-reported satisfaction over the study period.
Who should consider this trial
Good fit: Adults in Malaysia aged 18 or older with clinically diagnosed mild to moderate atopic eczema (EASI 10–20) who are not using interfering topical or systemic treatments and have no contraindicating conditions could qualify.
Not a fit: People with severe eczema, those on active eczema medications, pregnant or breastfeeding women, individuals with autoimmune diseases, or anyone with known allergies to moisturizer ingredients are unlikely to receive benefit from this study.
Why it matters
Potential benefit: If successful, the lotion could reduce visible eczema lesions and improve skin comfort as a low-risk topical option.
How similar studies have performed: Previous clinical experience and trials of emollients and moisturizers have generally shown they can improve eczema symptoms and skin barrier function, so this approach is well-established rather than novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy Malaysian women and men * Age above 18 years old * Clinically diagnosed with eczema with mild to moderate severity on any parts of the body as evaluated by Eczema Area and Severity Index (EASI) (score 10-20). Exclusion Criteria: * History of allergies or adverse reactions to moisturizers or components of the specific products being tested * History of chronic allergies * Pregnant, breastfeeding women, or those planning pregnancy during the study period * Participants with documented autoimmune diseases. * Currently undergoing or requiring active drug treatment for atopic dermatitis or eczema * Use of any medication (topical or systemic) that could interfere with the study aim (e.g. corticosteroids, calcineurin inhibitors, methotrexate) 3 months prior to the start of the study treatment and throughout the study * Current participation in another interventional clinical study * Presence of dermatological or systemic disorder other than eczema that could interfere with study outcomes
Where this trial is running
Petaling Jaya, Selangor
- USMARI Research & Innovation Centre — Petaling Jaya, Selangor, Malaysia (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Eczema