Skin closure method and body image after gynecologic cancer surgery
Official title: Effect of Skin Closure Techniques on Body Image and Mood in Gynecologic Oncology Patients
Run by Başakşehir Çam & Sakura City Hospital · NCT07327125 · Data updated 2026-11-12
This trial will test whether closing the midline belly incision with hidden (subcuticular) stitches versus staples or interrupted stitches changes body image and mood in women having open gynecologic cancer surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 17 Years to 60 Years |
| Sex | Women only |
| Enrollment | 140 (estimated) |
| Sponsor | Başakşehir Çam & Sakura City Hospital Government |
| Locations | 1 site (Istanbul) |
| Status | Recruiting |
| Started | January 1, 2026 |
| Main results expected | January 1, 2028 |
| Study ends | March 1, 2028 |
| Registry record updated | April 14, 2026 |
| Trial ID | NCT07327125 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 18 or older scheduled for elective open gynecologic cancer surgery via a vertical midline laparotomy who can read and complete questionnaires and provide informed consent.
✕Probably not a fit
Patients having minimally invasive or emergency procedures, those with prior abdominal/pelvic radiotherapy, extreme BMI (<18 or >40), chronic immunosuppression, or cognitive/major psychiatric impairment were excluded and would not be eligible to benefit from the trial's findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized trial enrolls women undergoing elective open gynecologic surgery through a vertical midline incision and assigns them to either interrupted skin closure (staples or separate mattress sutures) or continuous subcuticular sutures. Participants complete validated patient-reported measures including the Body Image Scale (BIS) and the Hospital Anxiety and Depression Scale (HADS) to capture cosmetic satisfaction and mood. The study also tracks wound complication rates such as infection and dehiscence to confirm safety of the subcuticular technique. Outcomes will compare cosmetic and psychological results between the two closure methods.
Why it matters
Potential benefit: If successful, using subcuticular sutures could improve cosmetic satisfaction and body image and reduce anxiety or depression without increasing wound complications.
How similar studies have gone: Other surgical fields have reported better cosmetic outcomes with subcuticular sutures, but evidence specifically in gynecologic oncology is limited and mixed.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female participants aged 18 years or older. * Patients scheduled for elective open gynecologic surgery for suspected or confirmed gynecologic malignancy. * Surgery planned to be performed via a vertical midline laparotomy incision. * Literate patients capable of reading, understanding, and completing the Body Image Scale (BIS) and Hospital Anxiety and Depression Scale (HADS). * Patients who provide written informed consent to participate in the study. Exclusion Criteria: * History of prior radiotherapy to the abdominal or pelvic region. * Patients currently receiving chronic immunosuppressive therapy. * Body Mass Index (BMI) less than 18 kg/m\^2 or greater than 40 kg/m\^2. * Presence of cognitive impairment, dementia, or Alzheimer's disease. * Major psychiatric disorders that prevent the patient from understanding or completing the questionnaires. * Patients undergoing emergency surgery.
Where it's running
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Başakşehir Çam and Sakura City Hospital
Istanbul, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Bora Taşpınar, MD — Başakşehir Çam & Sakura City Hospital
- Study coordinator: mahmut yassa, MD
- Email: mahmut_yassa@hotmail.com
- Phone: +90 539 663 54 84
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.