Skin blood flow and capillary refill monitoring in ICU patients with circulatory failure

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Microcirculatory abnormalities are a major driver of organ hypoperfusion in septic and cardiogenic shock, and capillary refill time (CRT) is an easy bedside tool linked to outcomes. This prospective observational study will record the kinetics of CRT and local skin blood flow before and after routine hemodynamic interventions such as fluid challenges, vasopressor adjustments, or inotropic drugs. Eligible patients are those in the medical intensive care unit with acute circulatory failure related to sepsis or cardiac failure, excluding those with agitation, hemorrhagic shock, or severe skin lesions. Measurements will be performed as part of usual care at Saint-Antoine Hospital to describe how peripheral perfusion responds to common treatments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients in intensive care unit with acute circulatory failure related to sepsis or cardiac failure requiring therapeutic intervention

Exclusion Criteria:

* Agitation
* Hemorrhagic shock
* Severe skin lesions

Where it's running

• Saint -Antoine Hospital_Médecine Intensive Reanimation
  Paris, France Recruiting

Study contacts

• Study coordinator: Hafid Ait-Oufella
• Email: hafid.aitoufella@aphp.fr
• Phone: +33612011940

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Femoral vein-to-artery diameter ratio to predict fluid responsiveness

  This project will test whether a bedside ultrasound measurement of the femoral vein-to-artery diameter ratio can tell if mechanically ventilated ICU patients with acute circulatory failure or shock will increase their cardiac output after a 500 mL fluid bolus.

  Recruiting Istanbul University - Cerrahpasa · Istanbul, Istanbul · NCT07546656

• Fluid balance guided by mVExUS in ICU patients on CRRT with acute kidney injury

  This trial tests whether using modified venous excess ultrasound (mVExUS) to guide fluid removal in ICU patients on CRRT with AKI can achieve a better fluid balance in the first 72 hours compared with standard care.

  Recruiting Chulalongkorn University · Bangkok and 1 other locations · NCT07346118

• Simplified electrical cardiometry test to predict which critically ill children will respond to fluids

  This project tests whether a quick, noninvasive electrical cardiometry measurement during a brief abdominal compression can see if critically ill children (≤8 years) will benefit from a 10 ml/kg fluid bolus.

  Recruiting University Hospital, Bordeaux · Le Plessis-Robinson, France and 3 other locations · NCT07522580

• How end-tidal CO2 changes during a leg raise help predict if fluids will help ICU patients

  This study checks if small increases in exhaled CO2 during a passive leg raise can tell doctors which critically ill, mechanically ventilated patients will respond to a fluid bolus.

  Recruiting Izmir Katip Celebi University · Izmir · NCT07304648

• Beacons for ICU: extra clinician alerts in ICU sub-units

  This study tests whether adding the ICU Beacon clinician awareness system to standard ICU care improves outcomes for adults with respiratory or circulatory failure compared with standard care alone.

  Recruiting ETH Zurich · Bern · NCT07119411

• Comparing blood thinners for patients on ECMO support

  This study is testing whether two different blood thinners, argatroban and enoxaparin, can work as well as the usual treatment, heparin, for patients on ECMO support.

  Recruiting Phase 4 Medical University of Vienna · Vienna, State of Vienna · NCT06442267

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.