Single-visit versus multiple-visit cervical cancer screen-and-treat for women with HIV in Foumban, Cameroon

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional program compares a single-visit screen-and-treat approach with a differentiated multiple-visit delivery model for HPV-based cervical cancer screening among women living with HIV at a district hospital. Enrolled participants (women on antiretroviral therapy who live in the hospital catchment area) will receive HPV testing, visual triage, and treatment when indicated, and the study will measure completion at each step of the screening cascade. The study also examines implementation outcomes such as feasibility and acceptability and includes sub-studies to refine the differentiated delivery model. The work is conducted at Foumban hospital in Cameroon with partners from regional and international research institutions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* HIV infection
* receiving antiretroviral therapy
* living in the department of the study hospital

Exclusion Criteria:

* ongoing pregnancy
* hysterectomy
* treatment of cervical lesion in the past 12 months
* Expected follow-up difficulties: planned absence that could interfere with the participation in the study (e.g., travel abroad, relocation, imminent transfer, etc.);
* Any pathology or concomitant treatment which, in the opinion of the investigators, contraindicates participation or prevents satisfactory participation in the study Inclusion deferred if
* menstrual bleeding
* post-partum (\<12 weeks after delivery)
* clinicla signs of cervical or pelvic infection

Where it's running

• Foumban hospital
  Foumban, Cameroon Recruiting

Study contacts

• Principal investigator: Joëlle Sobngwi, MD, PhD — RSD Institute
• Study coordinator: Andre-Pascal Goura, MD
• Email: cdpoptitri@gmail.com
• Phone: +227679336464

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Mobile HPV testing versus centralized screening to prevent cervical cancer in women living with HIV in western Cameroon

  This project tests whether bringing a mobile team that does on-site HPV testing, immediate visual check, and same-day treatment finds and treats cervical precancers more completely than sending women to central screening centers for women living with HIV aged 25–49.

  Recruiting at 6 sites Institut de Recherche pour le Developpement · Bafoussam and 5 other locations · NCT07181278

• Home-based cervical cancer self-sampling with education for women living with HIV in Ghana

  This study tests a home-based HPV self-sampling approach plus a 3R communication plan to help women with HIV in Ghana screen for cervical cancer.

  Recruiting Baylor University · Cape Coast, Central Region · NCT06800664

• Risk of cervical cancer after HPV detection in healthy women

  This study tests how likely it is for cervical cancer to develop after different HPV detection patterns in healthy women who undergo HPV-based screening.

  Recruiting Karolinska Institutet · Stockholm · NCT07850128

• Routine shallow-coverage Whole Genome Sequencing of Cervical Smears to See if Ovarian Cancer is Found Earlier

  Researchers test whether analyzing DNA from cervical smears with shallow whole-genome sequencing can help detect high-grade serous ovarian cancer early in patients undergoing treatment for this cancer.

  Recruiting Institut Claudius Regaud · Toulouse · NCT07821879

• Project SHIELD 2.0: Police Education to Support Public Health in Kentucky

  Aimed at police in Kentucky, this program tests whether SHIELD training given to officers, with health workers helping deliver it, can reduce drug-related arrests and steer people who use drugs toward MOUD and other health services.

  Recruiting Johns Hopkins Bloomberg School of Public Health · Lexington, Kentucky · NCT07804121

• New ways to diagnose lymphoma and multicentric Castleman disease in people living with HIV

  This study tests a quick, point-of-care nucleic acid test to help diagnose lymphoma and multicentric Castleman disease in people living with HIV in sub-Saharan Africa.

  Recruiting Indiana University · Lilongwe · NCT07793006

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.